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Magt1 Gene Detail
Summary
  • Symbol
    Magt1
  • Name
    magnesium transporter 1
  • Synonyms
    2410001C15Rik, 2610529C04Rik, 2810482I07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914325
    NCBI Gene: 67075
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:105011690-105055408 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 47.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    912 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914325
 protein coding gene ChrX:105011690-105055512 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036000
 protein coding gene ChrX:102749881-102794161 (-)
A/J MGP_AJ_G0035979
 protein coding gene ChrX:102519007-102563717 (-)
AKR/J MGP_AKRJ_G0035898
 protein coding gene ChrX:105807917-105854809 (-)
BALB/cJ MGP_BALBcJ_G0035969
 protein coding gene ChrX:101361881-101406216 (-)
C3H/HeJ MGP_C3HHeJ_G0035676
 protein coding gene ChrX:103186817-103231346 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036496
 protein coding gene ChrX:105683191-105728836 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033324
 protein coding gene ChrX:99990533-100035769 (-)
CAST/EiJ MGP_CASTEiJ_G0034963
 protein coding gene ChrX:87330501-87376332 (-)
CBA/J MGP_CBAJ_G0035651
 protein coding gene ChrX:108998639-109044413 (-)
DBA/2J MGP_DBA2J_G0035805
 protein coding gene ChrX:101812195-101856250 (-)
FVB/NJ MGP_FVBNJ_G0035746
 protein coding gene ChrX:101120114-101169894 (-)
LP/J MGP_LPJ_G0035898
 protein coding gene ChrX:103700648-103749795 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035778
 protein coding gene ChrX:113680542-113730570 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036522
 protein coding gene ChrX:102386442-102430540 (-)
PWK/PhJ MGP_PWKPhJ_G0034659
 protein coding gene ChrX:84861911-84907971 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034488
 protein coding gene ChrX:88069448-88114025 (-)
WSB/EiJ MGP_WSBEiJ_G0035101
 protein coding gene ChrX:101087542-101133007 (-)



Homology
more
  • Human Ortholog
    MAGT1, magnesium transporter 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGT1, magnesium transporter 1
  • Synonyms
    bA217H1.1, CDG1CC, IAP, MRX95, OST3B, PRO0756, SLC58A1, XMEN
  • Links
    NCBI Gene ID: 84061
    neXtProt AC: NX_Q9H0U3
    UniProt: Q9H0U3

  • Chr Location
    Xq21.1; chrX:77825747-77899271 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Magt1 mouse models; 2 with human MAGT1 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 3 alleles in 3 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice hemizygous for one gene trap allele exhibit decreased T cell number and increased B cell numbers with increased activation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67075 NCBI Gene Model | MGI Sequence Detail 43719 C57BL/6J ±  kb
    transcript NM_001190409 RefSeq | MGI Sequence Detail 4427 C57BL/6  
    polypeptide Q9CQY5 UniProt | EBI | MGI Sequence Detail 335 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000010088 magnesium transporter protein 1
      (term hierarchy)
    • InterPro Domains
      IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
      IPR036249 Thioredoxin-like superfamily
    • GlyGen
      Q9CQY5 2 sites, 2 N-linked glycans (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1914493, MGI:1917001
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 5
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory