Zbtb8os MGI Mouse Gene Detail - MGI:1914356 - zinc finger and BTB domain containing 8 opposite strand

Symbol

Zbtb8os
Name

zinc finger and BTB domain containing 8 opposite strand
Synonyms

2010001H09Rik, 2310028N13Rik, Arch

Feature Type

protein coding gene
IDs

MGI:1914356
NCBI Gene: 67106
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr4:129229325-129243664 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 63.26 cM, cytoband D2.3
Mapping Data

3 experiments

SNPs within 2kb

223 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914356	protein coding gene	Chr4:129229325-129248340 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028820	protein coding gene	Chr4:131237602-131262835 (+)
A/J	MGP_AJ_G0028779	protein coding gene	Chr4:126010258-126028986 (+)
AKR/J	MGP_AKRJ_G0028732	protein coding gene	Chr4:129512133-129532097 (+)
BALB/cJ	MGP_BALBcJ_G0028802	protein coding gene	Chr4:126601675-126621004 (+)
C3H/HeJ	MGP_C3HHeJ_G0028516	protein coding gene	Chr4:129565844-129586114 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029244	protein coding gene	Chr4:136184800-136208194 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026517	protein coding gene	Chr4:119140467-119159439 (+)
CAST/EiJ	MGP_CASTEiJ_G0027949	protein coding gene	Chr4:127748509-127767352 (+)
CBA/J	MGP_CBAJ_G0028482	protein coding gene	Chr4:139498260-139533019 (+)
DBA/2J	MGP_DBA2J_G0028631	protein coding gene	Chr4:126440556-126458849 (+)
FVB/NJ	MGP_FVBNJ_G0028598	protein coding gene	Chr4:125205637-125225401 (+)
LP/J	MGP_LPJ_G0028732	protein coding gene	Chr4:131528747-131548046 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028624	protein coding gene	Chr4:144398229-144420109 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029282	protein coding gene	Chr4:129885566-129907189 (+)
PWK/PhJ	MGP_PWKPhJ_G0027670	protein coding gene	Chr4:123023054-123045034 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027497	protein coding gene	Chr4:125746460-125764607 (+)
WSB/EiJ	MGP_WSBEiJ_G0028029	protein coding gene	Chr4:130001010-130023397 (+)

Human Ortholog

ZBTB8OS, zinc finger and BTB domain containing 8 opposite strand

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZBTB8OS, zinc finger and BTB domain containing 8 opposite strand
Synonyms

ARCH, ARCH2
Links

HGNC:24094

NCBI Gene ID: 339487

neXtProt AC: NX_Q8IWT0

UniProt: Q8IWT0
Chr Location

1p35.1; chr1:32600172-32650932 (-) GRCh38

MGI Vertebrate Homology

Zbtb8os stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZBTB8OS
Gene Tree

Zbtb8os

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

41
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

34
Radiation induced

1
Targeted

3
Genomic Mutations

4 involving Zbtb8os
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

48 strains or lines available

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All GO Annotations

7
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

710
Tissues

2
cDNA Data

28
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase zbtb8os

ZFIN zbtb8os

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All Sequences

54
RefSeq

6
UniProt

4
CCDS

CCDS18689.1

Ensembl

ENSMUSG00000057572 (Evidence)
NCBI Gene

67106

			Length	Strain/Species	Flank
genomic	67106	NCBI Gene Model \| MGI Sequence Detail	14340	C57BL/6J	± kb
transcript	NM_025970	RefSeq \| MGI Sequence Detail	3560	C57BL/6
polypeptide	Q505B7	UniProt \| EBI \| MGI Sequence Detail	168	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000017596 protein archease

(term hierarchy)
InterPro Domains

IPR002804 Archease

IPR023572 Archease domain

IPR036820 Archease domain superfamily

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All nucleic 30

cDNA 29

Primer pair 1

Microarray probesets 6

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MGI:1916849, MGI:2140990

Summaries

All 41

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 14
Earliest

J:24458 Bar I, et al., A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments. Genomics. 1995 Apr 10;26(3):543-9
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Zbtb8os:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr39141	Chr4:129229386-129229438 (+)	87 bp
Tssr39142	Chr4:129229755-129229780 (+)	443 bp
Tssr39143	Chr4:129229809-129229834 (+)	497 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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