Eef1g MGI Mouse Gene Detail - MGI:1914410 - eukaryotic translation elongation factor 1 gamma

Symbol

Eef1g
Name

eukaryotic translation elongation factor 1 gamma
Synonyms

2610301D06Rik, EF1G

Feature Type

protein coding gene
IDs

MGI:1914410
NCBI Gene: 67160
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr19:8944405-8955544 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 6.04 cM
Mapping Data

1 experiment

SNPs within 2kb

323 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914410	protein coding gene	Chr19:8944405-8955843 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024827	protein coding gene	Chr19:6255821-6267079 (+)
A/J	MGP_AJ_G0024795	protein coding gene	Chr19:5920269-5932195 (+)
AKR/J	MGP_AKRJ_G0024770	protein coding gene	Chr19:6020322-6033921 (+)
BALB/cJ	MGP_BALBcJ_G0024795	protein coding gene	Chr19:6029681-6041402 (+)
C3H/HeJ	MGP_C3HHeJ_G0024561	protein coding gene	Chr19:6108125-6119422 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025242	protein coding gene	Chr19:6392350-6408952 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022671	protein coding gene	Chr19:6176401-6188027 (+)
CAST/EiJ	MGP_CASTEiJ_G0024034	protein coding gene	Chr19:5760371-5773904 (+)
CBA/J	MGP_CBAJ_G0024535	protein coding gene	Chr19:6510666-6524702 (+)
DBA/2J	MGP_DBA2J_G0024662	protein coding gene	Chr19:5754665-5766951 (+)
FVB/NJ	MGP_FVBNJ_G0024629	protein coding gene	Chr19:5826117-5837371 (+)
LP/J	MGP_LPJ_G0024749	protein coding gene	Chr19:6154426-6165687 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024656	protein coding gene	Chr19:6371268-6384452 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025291	protein coding gene	Chr19:6068304-6084161 (+)
PWK/PhJ	MGP_PWKPhJ_G0023779	protein coding gene	Chr19:5428160-5440157 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023584	protein coding gene	Chr19:5675491-5689550 (+)
WSB/EiJ	MGP_WSBEiJ_G0024096	protein coding gene	Chr19:6038025-6049769 (+)

Human Ortholog

EEF1G, eukaryotic translation elongation factor 1 gamma

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

EEF1G, eukaryotic translation elongation factor 1 gamma
Synonyms

EF1G, GIG35
Links

HGNC:3213

NCBI Gene ID: 1937

neXtProt AC: NX_P26641

UniProt: P26641
Chr Location

11q12.3; chr11:62559596-62574086 (-) GRCh38

MGI Vertebrate Homology

Eef1g stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: EEF1G
Gene Tree

Eef1g

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

63
Endonuclease-mediated

2
Gene trapped

61
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

50 strains or lines available

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All GO Annotations

9
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

718
Tissues

7
cDNA Data

32
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase eef1g

ZFIN eef1g

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All Sequences

67
RefSeq

2
UniProt

3
CCDS

CCDS29563.1

Ensembl

ENSMUSG00000071644 (Evidence)
NCBI Gene

67160

			Length	Strain/Species	Flank
genomic	67160	NCBI Gene Model \| MGI Sequence Detail	11140	C57BL/6J	± kb
transcript	NM_026007	RefSeq \| MGI Sequence Detail	1565	C57BL/6
polypeptide	Q9D8N0	UniProt \| EBI \| MGI Sequence Detail	437	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000006908 elongation factor 1-gamma

(term hierarchy)
InterPro Domains

IPR001662 Elongation factor 1B gamma, C-terminal

IPR036433 Elongation factor EF1B gamma, C-terminal domain superfamily

IPR050802 Elongation Factors and Glutathione S-transferases

IPR004046 Glutathione S-transferase, C-terminal

IPR036282 Glutathione S-transferase, C-terminal domain superfamily

IPR010987 Glutathione S-transferase, C-terminal-like

IPR004045 Glutathione S-transferase, N-terminal

IPR040079 Glutathione transferase family

IPR036249 Thioredoxin-like superfamily
GlyGen

Q9D8N0 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)

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All nucleic 34

cDNA 32

Primer pair 2

Microarray probesets 3

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MGI:2143967

Summaries

All 34

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 7
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:147173 Sultana DA, et al., Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood. 2009 Mar 26;113(13):2976-87

TSS for Eef1g:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr154905	Chr19:8944085-8944099 (+)	-313 bp
Tssr154906	Chr19:8944363-8944383 (+)	-32 bp
Tssr154907	Chr19:8944395-8944414 (+)	0 bp
Tssr154908	Chr19:8944428-8944441 (+)	30 bp
Tssr154909	Chr19:8944443-8944466 (+)	50 bp
Tssr154910	Chr19:8944473-8944535 (+)	99 bp
Tssr154911	Chr19:8944539-8944572 (+)	151 bp
Tssr154912	Chr19:8947924-8947929 (+)	3,522 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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