Gstcd MGI Mouse Gene Detail - MGI:1914803 - glutathione S-transferase, C-terminal domain containing

Symbol

Gstcd
Name

glutathione S-transferase, C-terminal domain containing
Synonyms

4933434L15Rik

Feature Type

protein coding gene
IDs

MGI:1914803
NCBI Gene: 67553
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr3:132687513-132797794 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 61.54 cM, cytoband H2
Mapping Data

2 experiments

SNPs within 2kb

2705 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914803	protein coding gene	Chr3:132687511-132797800 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027895	protein coding gene	Chr3:135771154-135876612 (-)
A/J	MGP_AJ_G0027853	protein coding gene	Chr3:130982484-131089062 (-)
AKR/J	MGP_AKRJ_G0027818	protein coding gene	Chr3:134397806-134512922 (-)
BALB/cJ	MGP_BALBcJ_G0027866	protein coding gene	Chr3:130815531-130924810 (-)
C3H/HeJ	MGP_C3HHeJ_G0027595	protein coding gene	Chr3:134789414-134892740 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028309	protein coding gene	Chr3:140524383-140632798 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025647	protein coding gene	Chr3:126414114-126517595 (-)
CAST/EiJ	MGP_CASTEiJ_G0027051	protein coding gene	Chr3:134541685-134656985 (-)
CBA/J	MGP_CBAJ_G0027571	protein coding gene	Chr3:145272693-145403520 (-)
DBA/2J	MGP_DBA2J_G0027711	protein coding gene	Chr3:130145679-130251063 (-)
FVB/NJ	MGP_FVBNJ_G0027678	protein coding gene	Chr3:127722305-127831753 (-)
LP/J	MGP_LPJ_G0027821	protein coding gene	Chr3:137245162-137349388 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027709	protein coding gene	Chr3:153242439-153372948 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028367	protein coding gene	Chr3:134068148-134167400 (-)
PWK/PhJ	MGP_PWKPhJ_G0026775	protein coding gene	Chr3:129918451-130019492 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026600	protein coding gene	Chr3:132138255-132243458 (-)
WSB/EiJ	MGP_WSBEiJ_G0027130	protein coding gene	Chr3:134825303-134937205 (-)

Human Ortholog

GSTCD, glutathione S-transferase C-terminal domain containing

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GSTCD, glutathione S-transferase C-terminal domain containing
Links

HGNC:25806

NCBI Gene ID: 79807

neXtProt AC: NX_Q8NEC7

UniProt: Q8NEC7
Chr Location

4q24; chr4:105708778-105847725 (+) GRCh38

MGI Vertebrate Homology

Gstcd stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: GSTCD
Gene Tree

Gstcd

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References

1 with disease annotations

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Phenotype Summary

5 phenotypes from 1 allele in 2 genetic backgrounds
21 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

44
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

37
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Gstcd
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

57 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

7
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

2
cDNA Data

29
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase gstcd

ZFIN gstcd

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All Sequences

45
RefSeq

5
UniProt

1
CCDS

CCDS17847.1

Ensembl

ENSMUSG00000028018 (Evidence)
NCBI Gene

67553

			Length	Strain/Species	Flank
genomic	ENSMUSG00000028018	Ensembl Gene Model \| MGI Sequence Detail	110282	C57BL/6J	± kb
transcript	ENSMUST00000029651	Ensembl \| MGI Sequence Detail	3503	Not Applicable
polypeptide	ENSMUSP00000029651	Ensembl \| MGI Sequence Detail	634	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000029522 glutathione S-transferase C-terminal domain-containing protein

(term hierarchy)
InterPro Domains

IPR004046 Glutathione S-transferase, C-terminal

IPR036282 Glutathione S-transferase, C-terminal domain superfamily

IPR010987 Glutathione S-transferase, C-terminal-like

IPR025714 Methyltransferase domain

IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
GlyGen

Q5RL51 1 site, 1 O-linked glycan (1 site)

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All nucleic 30

cDNA 30

Microarray probesets 3

Summaries

All 44

Developmental Gene Expression 1

Diseases 1

Gene Ontology 5

Phenotypes 21
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Gstcd:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr35749	Chr3:132798139-132798155 (-)	-353 bp
Tssr35748	Chr3:132797806-132797815 (-)	-17 bp
Tssr35747	Chr3:132797790-132797800 (-)	-1 bp
Tssr35746	Chr3:132797559-132797608 (-)	210 bp
Tssr35745	Chr3:132797525-132797544 (-)	259 bp
Tssr35744	Chr3:132797497-132797523 (-)	284 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24