Gstcd Gene Detail

Summary

• Symbol
  Gstcd
• Name
  glutathione S-transferase, C-terminal domain containing
• Synonyms
  4933434L15Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1914803
  NCBI Gene: 67553
• Alliance
  gene page
• Transcription Start Sites
  6 TSS

Location &
Maps

• Sequence Map
  Chr3:132687513-132797794 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 61.54 cM, cytoband H2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  2705 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914803	protein coding gene	Chr3:132687511-132797800 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027895	protein coding gene	Chr3:135771154-135876612 (-)
A/J	MGP_AJ_G0027853	protein coding gene	Chr3:130982484-131089062 (-)
AKR/J	MGP_AKRJ_G0027818	protein coding gene	Chr3:134397806-134512922 (-)
BALB/cJ	MGP_BALBcJ_G0027866	protein coding gene	Chr3:130815531-130924810 (-)
C3H/HeJ	MGP_C3HHeJ_G0027595	protein coding gene	Chr3:134789414-134892740 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028309	protein coding gene	Chr3:140524383-140632798 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025647	protein coding gene	Chr3:126414114-126517595 (-)
CAST/EiJ	MGP_CASTEiJ_G0027051	protein coding gene	Chr3:134541685-134656985 (-)
CBA/J	MGP_CBAJ_G0027571	protein coding gene	Chr3:145272693-145403520 (-)
DBA/2J	MGP_DBA2J_G0027711	protein coding gene	Chr3:130145679-130251063 (-)
FVB/NJ	MGP_FVBNJ_G0027678	protein coding gene	Chr3:127722305-127831753 (-)
LP/J	MGP_LPJ_G0027821	protein coding gene	Chr3:137245162-137349388 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027709	protein coding gene	Chr3:153242439-153372948 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028367	protein coding gene	Chr3:134068148-134167400 (-)
PWK/PhJ	MGP_PWKPhJ_G0026775	protein coding gene	Chr3:129918451-130019492 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026600	protein coding gene	Chr3:132138255-132243458 (-)
WSB/EiJ	MGP_WSBEiJ_G0027130	protein coding gene	Chr3:134825303-134937205 (-)

Homology

• Human Ortholog
  GSTCD, glutathione S-transferase C-terminal domain containing

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  GSTCD, glutathione S-transferase C-terminal domain containing
  
• Links
  HGNC:25806

  NCBI Gene ID: 79807

  neXtProt AC: NX_Q8NEC7

  UniProt: Q8NEC7

  
  
• Chr Location
  4q24; chr4:105708778-105847725 (+)  GRCh38

---

• MGI Vertebrate Homology
  Gstcd stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: GSTCD
• Gene Tree
  Gstcd
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 2 genetic backgrounds
  21 phenotype references
  

• All Mutations and Alleles
  44
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Gene trapped
  37
• Radiation induced
  1
• Targeted
  3
• Genomic Mutations
  2 involving Gstcd
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  57 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Gene Ontology
(GO)
Classifications

• All GO Annotations
  4
• GO References
  4

Expression

• Assay Results
  708
• Tissues
  2
• cDNA Data
  29
• Literature Summary
  1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase gstcd
  ZFIN gstcd

Sequences &
Gene Models

• All Sequences
  45
• RefSeq
  5
• UniProt
  1
• CCDS
  CCDS17847.1

• Ensembl
  ENSMUSG00000028018 (Evidence)
• NCBI Gene
  67553

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000028018	Ensembl Gene Model | MGI Sequence Detail	110282	C57BL/6J
transcript	ENSMUST00000029651	Ensembl | MGI Sequence Detail	3503	Not Applicable
polypeptide	ENSMUSP00000029651	Ensembl | MGI Sequence Detail	634	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000029522 glutathione S-transferase C-terminal domain-containing protein
  (term hierarchy)
• InterPro Domains
  IPR004046 Glutathione S-transferase, C-terminal
  IPR036282 Glutathione S-transferase, C-terminal domain superfamily
  IPR010987 Glutathione S-transferase, C-terminal-like
  IPR025714 Methyltransferase domain
  IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
• GlyGen
  Q5RL51 1 site, 1 O-linked glycan (1 site)

Molecular
Reagents

• All nucleic 30

  cDNA 30

  
  

  Microarray probesets 3

References

• Summaries
  All 44

  Developmental Gene Expression 1

  Diseases 1

  Gene Ontology 4

  Phenotypes 21
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Gstcd:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr35749	Chr3:132798139-132798155 (-)	-353 bp
Tssr35748	Chr3:132797806-132797815 (-)	-17 bp
Tssr35747	Chr3:132797790-132797800 (-)	-1 bp
Tssr35746	Chr3:132797559-132797608 (-)	210 bp
Tssr35745	Chr3:132797525-132797544 (-)	259 bp
Tssr35744	Chr3:132797497-132797523 (-)	284 bp