Ctxnd2 Gene Detail

Summary

• Symbol
  Ctxnd2
• Name
  cortexin domain containing 2
• Synonyms
  4930558C23Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1914904
  NCBI Gene: 67654
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr3:95293769-95310143 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 40.74 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  400 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914904	protein coding gene	Chr3:95293769-95310152 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0006243	lincRNA gene	Chr3:96116679-96124984 (-)
A/J	MGP_AJ_G0006235	lincRNA gene	Chr3:93134207-93145562 (-)
AKR/J	MGP_AKRJ_G0006211	lincRNA gene	Chr3:95293040-95304142 (-)
BALB/cJ	MGP_BALBcJ_G0006211	lincRNA gene	Chr3:92905071-92917679 (-)
C3H/HeJ	MGP_C3HHeJ_G0006161	lincRNA gene	Chr3:95568111-95584025 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0006375	lincRNA gene	Chr3:99672701-99688669 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0005678	lincRNA gene	Chr3:89489901-89501018 (-)
CAST/EiJ	MGP_CASTEiJ_G0006095	lincRNA gene	Chr3:94854469-94866735 (-)
CBA/J	MGP_CBAJ_G0006146	lincRNA gene	Chr3:103309378-103325546 (-)
DBA/2J	MGP_DBA2J_G0006165	lincRNA gene	Chr3:92423252-92435255 (-)
FVB/NJ	MGP_FVBNJ_G0006188	lincRNA gene	Chr3:90499818-90516442 (-)
LP/J	MGP_LPJ_G0006247	lincRNA gene	Chr3:97428503-97436975 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0006179	lincRNA gene	Chr3:109408280-109420285 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0006379	lincRNA gene	Chr3:94942732-94957444 (-)
PWK/PhJ	MGP_PWKPhJ_G0006039	lincRNA gene	Chr3:92302903-92314258 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0005947	lincRNA gene	Chr3:93230110-93241085 (-)
WSB/EiJ	MGP_WSBEiJ_G0006142	lincRNA gene	Chr3:95324949-95335826 (-)

Homology

• Human Ortholog
  CTXND2, cortexin domain containing 2

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CTXND2, cortexin domain containing 2
  
• Links
  HGNC:53440

  NCBI Gene ID: 100996521

  UniProt: A0A1B0GV90

  
  
• Chr Location
  chr1:150887136-150913292 (+)  GRCh38

---

• MGI Vertebrate Homology
  Ctxnd2 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: CTXND2
• Gene Tree
  Ctxnd2
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  7 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Gene trapped
  3
• Radiation induced
  1
• Genomic Mutations
  2 involving Ctxnd2
• Find Mice (IMSR)
  17 strains or lines available

Males homozygous for a null allele show normal male fertility.

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  7

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• UniProt
  1

• Ensembl
  ENSMUSG00000105734 (Evidence)
• NCBI Gene
  67654

Representative Sequences			Length	Strain/Species
genomic	67654	NCBI Gene Model | MGI Sequence Detail	16375	C57BL/6J
transcript	NM_001384190	RefSeq | MGI Sequence Detail	725	C57BL/6
polypeptide	A0A1B0GQX3	UniProt | EBI | MGI Sequence Detail	59	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059659 cortexin domain containing 2
  (term hierarchy)
• InterPro Domains
  IPR020066 Cortexin

Molecular
Reagents

• All nucleic 9

  cDNA 9

Other
Accession IDs

MGI:7284179

References

• Summaries
  All 18

  Diseases 1

  Gene Ontology 1

  Phenotypes 7
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:315008 Oyama Y, et al., CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice. Asian J Androl. 2021 Jul 16;

TSS for Ctxnd2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34480	Chr3:95310106-95310162 (-)	9 bp
Tssr34479	Chr3:95310092-95310097 (-)	48 bp
Tssr34478	Chr3:95310086-95310091 (-)	54 bp