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Ccdc121 Gene Detail
Summary
  • Symbol
    Ccdc121
  • Name
    coiled-coil domain containing 121
  • Synonyms
    4930548H24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914906
    NCBI Gene: 67656
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:31643205-31645820 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 17.27 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    165 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914906
 protein coding gene Chr5:31643084-31645820 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029426
 protein coding gene Chr5:29502811-29505547 (+)
A/J MGP_AJ_G0029392
 protein coding gene Chr5:28557567-28560303 (+)
AKR/J MGP_AKRJ_G0029342
 protein coding gene Chr5:29709524-29712260 (+)
BALB/cJ MGP_BALBcJ_G0029403
 protein coding gene Chr5:29088585-29091321 (+)
C3H/HeJ MGP_C3HHeJ_G0029124
 protein coding gene Chr5:29717833-29720569 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029856
 protein coding gene Chr5:31335351-31338087 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027094
 protein coding gene Chr5:26159466-26162021 (+)
CAST/EiJ MGP_CASTEiJ_G0028534
 protein coding gene Chr5:28757448-28760184 (+)
CBA/J MGP_CBAJ_G0029092
 protein coding gene Chr5:31959786-31962522 (+)
DBA/2J MGP_DBA2J_G0029241
 protein coding gene Chr5:28719114-28721850 (+)
FVB/NJ MGP_FVBNJ_G0029199
 protein coding gene Chr5:28139839-28142575 (+)
LP/J MGP_LPJ_G0029326
 protein coding gene Chr5:29958746-29961482 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029228
 protein coding gene Chr5:32791356-32795099 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029890
 protein coding gene Chr5:29206702-29209438 (+)
PWK/PhJ MGP_PWKPhJ_G0028259
 protein coding gene Chr5:27872713-27875634 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028090
 protein coding gene Chr5:28667176-28669947 (+)
WSB/EiJ MGP_WSBEiJ_G0028615
 protein coding gene Chr5:29271862-29274598 (+)



Homology
more
  • Human Ortholog
    CCDC121, coiled-coil domain containing 121
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC121, coiled-coil domain containing 121
  • Links
    NCBI Gene ID: 79635
    neXtProt AC: NX_Q6ZUS5
    UniProt: Q6ZUS5

  • Chr Location
    2p23.3; chr2:27625638-27629012 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    5 involving Ccdc121
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    23 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67656 NCBI Gene Model | MGI Sequence Detail 2616 C57BL/6J ±  kb
transcript NM_026296 RefSeq | MGI Sequence Detail 1639 C57BL/6  
polypeptide NP_080572 RefSeq | MGI Sequence Detail 437 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR032777 Domain of unknown function DUF4515
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140869, MGI:6886236
References
more
  • Summaries
    All 44
    Diseases 1
    Phenotypes 26
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:125425 Howell GR, et al., Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics. 2007 Feb;175(2):699-707
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory