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Hapln3 Gene Detail
Summary
  • Symbol
    Hapln3
  • Name
    hyaluronan and proteoglycan link protein 3
  • Synonyms
    4930554N11Rik, Lpr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914916
    NCBI Gene: 67666
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:78764850-78780766 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 44.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    525 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914916
 protein coding gene Chr7:78764850-78783100 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032384
 protein coding gene Chr7:80966626-80986674 (-)
A/J MGP_AJ_G0032363
 protein coding gene Chr7:79118060-79133675 (-)
AKR/J MGP_AKRJ_G0032299
 protein coding gene Chr7:80808228-80823553 (-)
BALB/cJ MGP_BALBcJ_G0032375
 protein coding gene Chr7:78816526-78832083 (-)
C3H/HeJ MGP_C3HHeJ_G0032088
 protein coding gene Chr7:81472856-81489984 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032867
 protein coding gene Chr7:84162340-84180859 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029875
 protein coding gene Chr7:81668593-81683707 (-)
CAST/EiJ MGP_CASTEiJ_G0031416
 protein coding gene Chr7:72331979-72350789 (-)
CBA/J MGP_CBAJ_G0032054
 protein coding gene Chr7:86969377-86991940 (-)
DBA/2J MGP_DBA2J_G0032209
 protein coding gene Chr7:77701929-77718023 (-)
FVB/NJ MGP_FVBNJ_G0032164
 protein coding gene Chr7:77607318-77623431 (-)
LP/J MGP_LPJ_G0032290
 protein coding gene Chr7:82221595-82237089 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032201
 protein coding gene Chr7:87183924-87209902 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032885
 protein coding gene Chr7:80260866-80276451 (-)
PWK/PhJ MGP_PWKPhJ_G0031136
 protein coding gene Chr7:70858069-70874526 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030977
 protein coding gene Chr7:67250113-67265526 (-)
WSB/EiJ MGP_WSBEiJ_G0031534
 protein coding gene Chr7:80580854-80596302 (-)



Homology
more
  • Human Ortholog
    HAPLN3, hyaluronan and proteoglycan link protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HAPLN3, hyaluronan and proteoglycan link protein 3
  • Synonyms
    EXLD1, HsT19883
  • Links
    NCBI Gene ID: 145864
    neXtProt AC: NX_Q96S86
    UniProt: Q96S86

  • Chr Location
    15q26.1; chr15:88877294-88895597 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Hapln3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    23 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030606 Ensembl Gene Model | MGI Sequence Detail 15917 C57BL/6J ±  kb
transcript ENSMUST00000206092 Ensembl | MGI Sequence Detail 3358 Not Applicable  
polypeptide ENSMUSP00000146090 Ensembl | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Gene Ontology 4
    Phenotypes 16
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory