Luc7l3 MGI Mouse Gene Detail - MGI:1914934 - LUC7-like 3 (S. cerevisiae)

Symbol

Luc7l3
Name

LUC7-like 3 (S. cerevisiae)
Synonyms

3300001P08Rik

Feature Type

protein coding gene
IDs

MGI:1914934
NCBI Gene: 67684
Alliance

gene page
Transcription Start Sites

19 TSS

Sequence Map

Chr11:94181899-94213196 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 58.90 cM, cytoband C
Mapping Data

2 experiments

SNPs within 2kb

650 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914934	protein coding gene	Chr11:94178716-94213196 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0018953	protein coding gene	Chr11:96359074-96395083 (-)
A/J	MGP_AJ_G0018921	protein coding gene	Chr11:92516346-92550407 (-)
AKR/J	MGP_AKRJ_G0018891	protein coding gene	Chr11:95390049-95424922 (-)
BALB/cJ	MGP_BALBcJ_G0018894	protein coding gene	Chr11:92958537-92992602 (-)
C3H/HeJ	MGP_C3HHeJ_G0018708	protein coding gene	Chr11:95474235-95511231 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019346	protein coding gene	Chr11:99358029-99393748 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016977	protein coding gene	Chr11:90013522-90047766 (-)
CAST/EiJ	MGP_CASTEiJ_G0018263	protein coding gene	Chr11:96179089-96215347 (-)
CBA/J	MGP_CBAJ_G0018679	protein coding gene	Chr11:103483960-103520111 (-)
DBA/2J	MGP_DBA2J_G0018787	protein coding gene	Chr11:92091810-92126100 (-)
FVB/NJ	MGP_FVBNJ_G0018776	protein coding gene	Chr11:91510700-91544658 (-)
LP/J	MGP_LPJ_G0018857	protein coding gene	Chr11:96907645-96943873 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018803	protein coding gene	Chr11:103525817-103563625 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019386	protein coding gene	Chr11:95611300-95648855 (-)
PWK/PhJ	MGP_PWKPhJ_G0018033	protein coding gene	Chr11:93019625-93054019 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0017823	protein coding gene	Chr11:95281120-95314737 (-)
WSB/EiJ	MGP_WSBEiJ_G0018312	protein coding gene	Chr11:95492851-95528710 (-)

Human Ortholog

LUC7L3, LUC7 like 3 pre-mRNA splicing factor

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

LUC7L3, LUC7 like 3 pre-mRNA splicing factor
Synonyms

CRA, CREAP-1, CROP, hLuc7A, LUC7A, OA48-18
Links

HGNC:24309

NCBI Gene ID: 51747

neXtProt AC: NX_O95232

UniProt: O95232
Chr Location

17q21.33; chr17:50719565-50756219 (+) GRCh38

MGI Vertebrate Homology

Luc7l3 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: LUC7L3
Gene Tree

Luc7l3

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References

1 with disease annotations

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
19 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

49
Endonuclease-mediated

2
Gene trapped

42
Targeted

5
Genomic Mutations

3 involving Luc7l3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

43 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

16
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

749
Tissues

29
cDNA Data

13
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase luc7l3

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All Sequences

76
RefSeq

19
UniProt

4
CCDS

CCDS25252.1, CCDS88223.1, CCDS88224.1

Ensembl

ENSMUSG00000020863 (Evidence)
NCBI Gene

67684

			Length	Strain/Species	Flank
genomic	67684	NCBI Gene Model \| MGI Sequence Detail	31298	C57BL/6J	± kb
transcript	NR_155068	RefSeq \| MGI Sequence Detail	3665	C57BL/6
polypeptide	Q5SUF2	UniProt \| EBI \| MGI Sequence Detail	432	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000005895 cisplatin resistance-associated overexpressed protein

(term hierarchy)
InterPro Domains

IPR004882 Luc7-related
GlyGen

Q5SUF2 1 site, 1 O-linked glycan (1 site)

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All nucleic 13

cDNA 13

Microarray probesets 6

Summaries

All 43

Developmental Gene Expression 1

Diseases 1

Gene Ontology 6

Phenotypes 19
Earliest

J:2300 Charles CH, et al., cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene. 1992 Jan;7(1):187-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Luc7l3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr110159	Chr11:94212783-94212794 (-)	407 bp
Tssr110158	Chr11:94212736-94212769 (-)	443 bp
Tssr110157	Chr11:94212724-94212735 (-)	466 bp
Tssr110156	Chr11:94212269-94212320 (-)	901 bp
Tssr3644	Chr11:94208496-94208512 (-)	4,692 bp
Tssr110155	Chr11:94200510-94200523 (-)	12,679 bp
Tssr110154	Chr11:94200474-94200493 (-)	12,712 bp
Tssr110153	Chr11:94196121-94196125 (-)	17,073 bp
Tssr110152	Chr11:94194754-94194774 (-)	18,432 bp
Tssr110151	Chr11:94194694-94194717 (-)	18,490 bp
Tssr110150	Chr11:94193306-94193309 (-)	19,888 bp
Tssr110149	Chr11:94192398-94192411 (-)	20,791 bp
Tssr110148	Chr11:94190803-94190894 (-)	22,347 bp
Tssr110147	Chr11:94188666-94188713 (-)	24,506 bp
Tssr110146	Chr11:94188647-94188662 (-)	24,541 bp
Tssr110145	Chr11:94188609-94188645 (-)	24,569 bp
Tssr110144	Chr11:94187949-94187964 (-)	25,239 bp
Tssr110143	Chr11:94187789-94187809 (-)	25,397 bp
Tssr110142	Chr11:94185916-94185920 (-)	27,278 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24