2310057J18Rik MGI Mouse Gene Detail - MGI:1914969

Symbol

2310057J18Rik
Name

RIKEN cDNA 2310057J18 gene
Synonyms

2210414P04Rik

Feature Type

protein coding gene
IDs

MGI:1914969
NCBI Gene: 67719
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr10:28848284-28862299 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 16.46 cM, cytoband A4
Mapping Data

2 experiments

SNPs within 2kb

377 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914969	protein coding gene	Chr10:28848284-28862302 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017108	protein coding gene	Chr10:27127550-27144663 (-)
A/J	MGP_AJ_G0017085	protein coding gene	Chr10:26303569-26317718 (-)
AKR/J	MGP_AKRJ_G0017045	protein coding gene	Chr10:26727763-26741772 (-)
BALB/cJ	MGP_BALBcJ_G0017048	protein coding gene	Chr10:26398297-26412866 (-)
C3H/HeJ	MGP_C3HHeJ_G0016868	protein coding gene	Chr10:26952809-26966818 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017506	protein coding gene	Chr10:27928383-27945381 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015204	protein coding gene	Chr10:24819822-24834514 (-)
CAST/EiJ	MGP_CASTEiJ_G0016447	protein coding gene	Chr10:27024134-27038393 (-)
CBA/J	MGP_CBAJ_G0016842	protein coding gene	Chr10:29274820-29290907 (-)
DBA/2J	MGP_DBA2J_G0016947	protein coding gene	Chr10:26017058-26031512 (-)
FVB/NJ	MGP_FVBNJ_G0016942	protein coding gene	Chr10:25641296-25655291 (-)
LP/J	MGP_LPJ_G0017024	protein coding gene	Chr10:27092733-27114431 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016972	protein coding gene	Chr10:29382158-29399022 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017542	protein coding gene	Chr10:26627318-26643202 (-)
PWK/PhJ	MGP_PWKPhJ_G0016229	protein coding gene	Chr10:25781956-25796365 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0016013	protein coding gene	Chr10:26533018-26534830 (-)
WSB/EiJ	MGP_WSBEiJ_G0016510	protein coding gene	Chr10:26761202-26776095 (-)

Human Ortholog

C6orf58, chromosome 6 open reading frame 58

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C6orf58, chromosome 6 open reading frame 58
Synonyms

LEG1
Links

HGNC:20960

NCBI Gene ID: 352999

neXtProt AC: NX_Q6P5S2

UniProt: Q6P5S2
Chr Location

chr6:127519455-127591820 (+) GRCh38

MGI Vertebrate Homology

2310057J18Rik stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: C6orf58
Gene Tree

2310057J18Rik

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

1
Targeted

2
Genomic Mutations

1 involving 2310057J18Rik
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

17 strains or lines available

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All GO Annotations

3
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

30

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN leg1.1, leg1.2

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All Sequences

59
RefSeq

2
UniProt

3
CCDS

CCDS23759.1

Ensembl

ENSMUSG00000015519 (Evidence)
NCBI Gene

67719

			Length	Strain/Species	Flank
genomic	ENSMUSG00000015519	Ensembl Gene Model \| MGI Sequence Detail	14016	C57BL/6J	± kb
transcript	ENSMUST00000015663	Ensembl \| MGI Sequence Detail	1238	Not Applicable
polypeptide	ENSMUSP00000015663	Ensembl \| MGI Sequence Detail	337	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000059862 protein LEG1 homolog

(term hierarchy)
InterPro Domains

IPR008499 Leg1
GlyGen

Q8C6C9 1 site

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All nucleic 30

cDNA 30

Microarray probesets 3

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MGI:1917654

Summaries

All 31

Gene Ontology 3

Phenotypes 9
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for 2310057J18Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr97157	Chr10:28862327-28862340 (-)	-35 bp
Tssr97156	Chr10:28862276-28862309 (-)	6 bp
Tssr97155	Chr10:28862205-28862255 (-)	69 bp
Tssr97154	Chr10:28861375-28861381 (-)	921 bp
Tssr97153	Chr10:28861310-28861319 (-)	984 bp
Tssr97152	Chr10:28849960-28849964 (-)	12,337 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24