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Tmem147 Gene Detail
Summary
  • Symbol
    Tmem147
  • Name
    transmembrane protein 147
  • Synonyms
    2010004E11Rik, 5033425B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915011
    NCBI Gene: 69804
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30427126-30428959 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.23 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915011
 protein coding gene Chr7:30427126-30428965 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032041
 protein coding gene Chr7:29736564-29738397 (-)
A/J MGP_AJ_G0032018
 protein coding gene Chr7:28926942-28928775 (-)
AKR/J MGP_AKRJ_G0031951
 protein coding gene Chr7:29668413-29670246 (-)
BALB/cJ MGP_BALBcJ_G0032025
 protein coding gene Chr7:29113863-29115696 (-)
C3H/HeJ MGP_C3HHeJ_G0031744
 protein coding gene Chr7:30125235-30127068 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032491
 protein coding gene Chr7:30704176-30706009 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029541
 protein coding gene Chr7:29949684-29951536 (-)
CAST/EiJ MGP_CASTEiJ_G0031078
 protein coding gene Chr7:23379082-23381395 (-)
CBA/J MGP_CBAJ_G0031710
 protein coding gene Chr7:32153157-32154990 (-)
DBA/2J MGP_DBA2J_G0031862
 protein coding gene Chr7:28655012-28656845 (-)
FVB/NJ MGP_FVBNJ_G0031819
 protein coding gene Chr7:28795128-28796961 (-)
LP/J MGP_LPJ_G0031943
 protein coding gene Chr7:30049263-30051096 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031855
 protein coding gene Chr7:31393577-31395410 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032519
 protein coding gene Chr7:29171099-29172932 (-)
PWK/PhJ MGP_PWKPhJ_G0030802
 protein coding gene Chr7:23696353-23698186 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030637
 protein coding gene Chr7:20180432-20182284 (-)
WSB/EiJ MGP_WSBEiJ_G0031188
 protein coding gene Chr7:29574836-29576669 (-)



Homology
more
  • Human Ortholog
    TMEM147, transmembrane protein 147
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM147, transmembrane protein 147
  • Synonyms
    NEDFLPH, NIFIE14
  • Links
    NCBI Gene ID: 10430
    neXtProt AC: NX_Q9BVK8
    UniProt: Q9BVK8

  • Chr Location
    19q13.12; chr19:35545600-35547526 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    38
  • cDNA Data
    96
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69804 NCBI Gene Model | MGI Sequence Detail 1834 C57BL/6J ±  kb
    transcript NM_027215 RefSeq | MGI Sequence Detail 868 C57BL/6  
    polypeptide Q9CQG6 UniProt | EBI | MGI Sequence Detail 224 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 97
      cDNA 97

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1917054
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory