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Shisa5 Gene Detail
Summary
  • Symbol
    Shisa5
  • Name
    shisa family member 5
  • Synonyms
    2310008D10Rik, 6430628I05Rik, Scotin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915044
    NCBI Gene: 66940
  • Alliance
    gene page
  • Transcription Start Sites
    28 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108867633-108886845 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.63 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    492 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915044
 protein coding gene Chr9:108867633-108886860 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035321
 protein coding gene Chr9:110992362-111014593 (+)
A/J MGP_AJ_G0035300
 protein coding gene Chr9:106913940-106930881 (+)
AKR/J MGP_AKRJ_G0035232
 protein coding gene Chr9:109604042-109624398 (+)
BALB/cJ MGP_BALBcJ_G0035294
 protein coding gene Chr9:106614196-106630986 (+)
C3H/HeJ MGP_C3HHeJ_G0035004
 protein coding gene Chr9:109997662-110014069 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035814
 protein coding gene Chr9:114019741-114041135 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032712
 protein coding gene Chr9:104319761-104337392 (+)
CAST/EiJ MGP_CASTEiJ_G0034315
 protein coding gene Chr9:109969354-109987677 (+)
CBA/J MGP_CBAJ_G0034972
 protein coding gene Chr9:118037656-118054036 (+)
DBA/2J MGP_DBA2J_G0035133
 protein coding gene Chr9:106366615-106386108 (+)
FVB/NJ MGP_FVBNJ_G0035081
 protein coding gene Chr9:105188561-105206079 (+)
LP/J MGP_LPJ_G0035209
 protein coding gene Chr9:111179633-111200250 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035120
 protein coding gene Chr9:119587970-119608066 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035835
 protein coding gene Chr9:109874039-109893832 (+)
PWK/PhJ MGP_PWKPhJ_G0034022
 protein coding gene Chr9:106703060-106722613 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033857
 protein coding gene Chr9:109939514-109958937 (+)
WSB/EiJ MGP_WSBEiJ_G0034436
 protein coding gene Chr9:109773502-109791183 (+)



Homology
more
  • Human Ortholog
    SHISA5, shisa family member 5
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHISA5, shisa family member 5
  • Synonyms
    SCOTIN
  • Links
    NCBI Gene ID: 51246
    neXtProt AC: NX_Q8N114
    UniProt: Q8N114

  • Chr Location
    3p21.31; chr3:48467798-48504826 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and exhibit no apparent phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    15
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025647 Ensembl Gene Model | MGI Sequence Detail 19213 C57BL/6J ±  kb
transcript ENSMUST00000112059 Ensembl | MGI Sequence Detail 1910 Not Applicable  
polypeptide ENSMUSP00000107690 Ensembl | MGI Sequence Detail 236 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 4
Other
Accession IDs
less
MGI:1914190
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326958 Sapir T, et al., Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex. Nat Commun. 2022 Jul 21;13(1):4209
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory