Lce1f Gene Detail

Summary

• Symbol
  Lce1f
• Name
  late cornified envelope 1F
• Synonyms
  1110055J05Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1915078
  NCBI Gene: 67828
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr3:92626003-92627657 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 40.14 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  202 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915078	protein coding gene	Chr3:92625992-92627657 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027512	protein coding gene	Chr3:93174009-93176481 (-)
A/J	MGP_AJ_G0027479	protein coding gene	Chr3:90243261-90245072 (-)
AKR/J	MGP_AKRJ_G0027444	protein coding gene	Chr3:92352608-92356154 (-)
BALB/cJ	MGP_BALBcJ_G0027487	protein coding gene	Chr3:90050414-90052079 (-)
C3H/HeJ	MGP_C3HHeJ_G0027227	protein coding gene	Chr3:92575236-92576931 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027931	protein coding gene	Chr3:96720929-96723390 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025279	protein coding gene	Chr3:86873516-86875122 (-)
CAST/EiJ	MGP_CASTEiJ_G0026673	protein coding gene	Chr3:91995369-91996949 (-)
CBA/J	MGP_CBAJ_G0027201	protein coding gene	Chr3:100043733-100045398 (-)
DBA/2J	MGP_DBA2J_G0027339	protein coding gene	Chr3:89570216-89571881 (-)
FVB/NJ	MGP_FVBNJ_G0027307	protein coding gene	Chr3:87733828-87735493 (-)
LP/J	MGP_LPJ_G0027447	protein coding gene	Chr3:94391127-94393254 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027332	protein coding gene	Chr3:106328079-106329774 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027990	protein coding gene	Chr3:92087455-92090552 (-)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0026224	protein coding gene	Chr3:90424749-90426154 (-)
WSB/EiJ	MGP_WSBEiJ_G0026756	protein coding gene	Chr3:92466328-92468023 (-)

Homology

• Human Ortholog
  LCE1A, late cornified envelope 1A

• Vertebrate Orthologs
  6

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  LCE1A, late cornified envelope 1A
  
• Synonyms
  LEP1
• Links
  HGNC:29459

  NCBI Gene ID: 353131

  neXtProt AC: NX_Q5T7P2

  UniProt: Q5T7P2

  
  
• Chr Location
  1q21.3; chr1:152827473-152828097 (+)  GRCh38

---

• Human Ortholog
  LCE1B, late cornified envelope 1B
  
• Synonyms
  LEP2, SPRL2A
• Links
  HGNC:16611

  NCBI Gene ID: 353132

  neXtProt AC: NX_Q5T7P3

  UniProt: Q5T7P3

  
  
• Chr Location
  1q21.3

---

• Human Ortholog
  LCE1C, late cornified envelope 1C
  
• Synonyms
  LEP3
• Links
  HGNC:29464

  NCBI Gene ID: 353133

  neXtProt AC: NX_Q5T751

  UniProt: Q5T751

  
  
• Chr Location
  1q21.3; chr1:152804832-152806651 (-)  GRCh38

---

• Human Ortholog
  LCE1E, late cornified envelope 1E
  
• Synonyms
  LEP5
• Links
  HGNC:29466

  NCBI Gene ID: 353135

  neXtProt AC: NX_Q5T753

  UniProt: Q5T753

  
  
• Chr Location
  1q21.3; chr1:152786214-152788426 (+)  GRCh38

---

• Human Ortholog
  LCE1F, late cornified envelope 1F
  
• Synonyms
  LEP6
• Links
  HGNC:29467

  NCBI Gene ID: 353137

  neXtProt AC: NX_Q5T754

  UniProt: Q5T754

  
  
• Chr Location
  1q21.3; chr1:152775140-152777024 (+)  GRCh38

---

• MGI Vertebrate Homology
  Lce1f stringent orthology
  5 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: LCE1A, LCE1B, LCE1C, LCE1E, LCE1F
• Gene Tree
  Lce1f
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 1 allele in 1 genetic background
  13 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Radiation induced
  1
• Targeted
  4
• Genomic Mutations
  2 involving Lce1f
• Incidental Mutations
  APF
• Find Mice (IMSR)
  12 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Gene Ontology
(GO)
Classifications

• All GO Annotations
  4
• GO References
  2

Expression

• Assay Results
  709
• Tissues
  3
• cDNA Data
  7
• Literature Summary
  1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS38515.1

• Ensembl
  ENSMUSG00000042124 (Evidence)
• NCBI Gene
  67828

Representative Sequences			Length	Strain/Species
genomic	67828	NCBI Gene Model | MGI Sequence Detail	1655	C57BL/6J
transcript	NM_026394	RefSeq | MGI Sequence Detail	768	C57BL/6
polypeptide	NP_080670	RefSeq | MGI Sequence Detail	147	C57BL/6

Protein
Information

• UniProt
  2 Sequences

Molecular
Reagents

• All nucleic 7

  cDNA 7

  
  

  Microarray probesets 2

References

• Summaries
  All 29

  Developmental Gene Expression 1

  Diseases 1

  Gene Ontology 2

  Phenotypes 13
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Lce1f:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34330	Chr3:92627688-92627694 (-)	-34 bp
Tssr34329	Chr3:92627651-92627666 (-)	-2 bp