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Tiprl Gene Detail
Summary
  • Symbol
    Tiprl
  • Name
    TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
  • Synonyms
    1810011K17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915087
    NCBI Gene: 226591
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:165039855-165064565 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 72.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    622 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915087
 protein coding gene Chr1:165039855-165110228 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016690
 protein coding gene Chr1:170691439-170718341 (-)
A/J MGP_AJ_G0016671
 protein coding gene Chr1:163725496-163751211 (-)
AKR/J MGP_AKRJ_G0016637
 protein coding gene Chr1:168684622-168710627 (-)
BALB/cJ MGP_BALBcJ_G0016632
 protein coding gene Chr1:164215757-164241375 (-)
C3H/HeJ MGP_C3HHeJ_G0016456
 protein coding gene Chr1:168905046-168931166 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017093
 protein coding gene Chr1:176412381-176443033 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014802
 protein coding gene Chr1:155640154-155663140 (-)
CAST/EiJ MGP_CASTEiJ_G0016036
 protein coding gene Chr1:168530997-168561116 (-)
CBA/J MGP_CBAJ_G0016431
 protein coding gene Chr1:182686145-182715270 (-)
DBA/2J MGP_DBA2J_G0016537
 protein coding gene Chr1:162617608-162642601 (-)
FVB/NJ MGP_FVBNJ_G0016535
 protein coding gene Chr1:161071102-161095307 (-)
LP/J MGP_LPJ_G0016608
 protein coding gene Chr1:171757295-171781620 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016560
 protein coding gene Chr1:190197817-190224011 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017129
 protein coding gene Chr1:168531523-168557949 (-)
PWK/PhJ MGP_PWKPhJ_G0015822
 protein coding gene Chr1:161817734-161849965 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015609
 protein coding gene Chr1:167408144-167431358 (-)
WSB/EiJ MGP_WSBEiJ_G0016098
 protein coding gene Chr1:168692524-168717799 (-)



Homology
more
  • Human Ortholog
    TIPRL, TOR signaling pathway regulator
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TIPRL, TOR signaling pathway regulator
  • Synonyms
    TIP, TIP41, TIPRL1
  • Links
    NCBI Gene ID: 261726
    neXtProt AC: NX_O75663
    UniProt: O75663

  • Chr Location
    1q24.2; chr1:168178962-168202109 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    42
  • cDNA Data
    81
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040843 Ensembl Gene Model | MGI Sequence Detail 24711 C57BL/6J ±  kb
transcript ENSMUST00000043235 Ensembl | MGI Sequence Detail 4380 Not Applicable  
polypeptide ENSMUSP00000037514 Ensembl | MGI Sequence Detail 271 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory