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Nsmce4a Gene Detail
Summary
  • Symbol
    Nsmce4a
  • Name
    NSE4 homolog A, SMC5-SMC6 complex component
  • Synonyms
    2410003A14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915122
    NCBI Gene: 67872
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:130134256-130149111 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 73.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    595 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915122
 protein coding gene Chr7:130134256-130174848 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033092
 protein coding gene Chr7:135055210-135097149 (-)
A/J MGP_AJ_G0033074
 protein coding gene Chr7:131380244-131422304 (-)
AKR/J MGP_AKRJ_G0033006
 protein coding gene Chr7:134861527-134903137 (-)
BALB/cJ MGP_BALBcJ_G0033075
 protein coding gene Chr7:131054149-131096653 (-)
C3H/HeJ MGP_C3HHeJ_G0032789
 protein coding gene Chr7:134733474-134775826 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033585
 protein coding gene Chr7:140264908-140305278 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030557
 protein coding gene Chr7:132540342-132581376 (-)
CAST/EiJ MGP_CASTEiJ_G0032119
 protein coding gene Chr7:126546983-126586338 (-)
CBA/J MGP_CBAJ_G0032762
 protein coding gene Chr7:145052304-145098006 (-)
DBA/2J MGP_DBA2J_G0032914
 protein coding gene Chr7:129382405-129424079 (-)
FVB/NJ MGP_FVBNJ_G0032867
 protein coding gene Chr7:129232058-129272909 (-)
LP/J MGP_LPJ_G0033008
 protein coding gene Chr7:136535678-136576235 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032899
 protein coding gene Chr7:146013175-146058860 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033604
 protein coding gene Chr7:133798764-133844427 (-)
PWK/PhJ MGP_PWKPhJ_G0031825
 protein coding gene Chr7:122445317-122485375 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031671
 protein coding gene Chr7:120622180-120664508 (-)
WSB/EiJ MGP_WSBEiJ_G0032230
 protein coding gene Chr7:134801556-134840601 (-)



Homology
more
  • Human Ortholog
    NSMCE4A, NSE4 homolog A, SMC5-SMC6 complex component
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NSMCE4A, NSE4 homolog A, SMC5-SMC6 complex component
  • Synonyms
    C10orf86, NS4EA, NSE4A
  • Links
    NCBI Gene ID: 54780
    neXtProt AC: NX_Q9NXX6
    UniProt: Q9NXX6

  • Chr Location
    10q26.13; chr10:121957091-121975217 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    108
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67872 NCBI Gene Model | MGI Sequence Detail 14856 C57BL/6J ±  kb
transcript NM_001162855 RefSeq | MGI Sequence Detail 1484 C57BL/6  
polypeptide NP_001156327 RefSeq | MGI Sequence Detail 381 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR014854 Non-structural maintenance of chromosome element 4, C-terminal
    IPR027786 Nse4/EID family
    IPR029225 Nse4/EID protein, Nse3/MAGE-binding domain
Molecular
Reagents
less
  • All nucleic 109
    cDNA 109

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory