Coq10b MGI Mouse Gene Detail - MGI:1915126

Symbol

Coq10b
Name

coenzyme Q10B
Synonyms

1500041J02Rik, 1700030I21Rik, 9530077A17Rik

Feature Type

protein coding gene
IDs

MGI:1915126
NCBI Gene: 67876
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr1:55091929-55111861 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 28.00 cM
Mapping Data

2 experiments

SNPs within 2kb

670 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915126	protein coding gene	Chr1:55091929-55111861 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016029	protein coding gene	Chr1:54763042-54782931 (+)
A/J	MGP_AJ_G0016012	protein coding gene	Chr1:52858251-52879182 (+)
AKR/J	MGP_AKRJ_G0015968	protein coding gene	Chr1:54295280-54315317 (+)
BALB/cJ	MGP_BALBcJ_G0015967	protein coding gene	Chr1:52909851-52932459 (+)
C3H/HeJ	MGP_C3HHeJ_G0015799	protein coding gene	Chr1:54539368-54559274 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016420	protein coding gene	Chr1:57031011-57050919 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014142	protein coding gene	Chr1:48955219-48975933 (+)
CAST/EiJ	MGP_CASTEiJ_G0015381	protein coding gene	Chr1:53812802-53832883 (+)
CBA/J	MGP_CBAJ_G0015771	protein coding gene	Chr1:58640311-58663150 (+)
DBA/2J	MGP_DBA2J_G0015872	protein coding gene	Chr1:52285199-52305461 (+)
FVB/NJ	MGP_FVBNJ_G0015874	protein coding gene	Chr1:51634053-51653867 (+)
LP/J	MGP_LPJ_G0015944	protein coding gene	Chr1:55589456-55612120 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015894	protein coding gene	Chr1:61750297-61771105 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016467	protein coding gene	Chr1:54245860-54265866 (+)
PWK/PhJ	MGP_PWKPhJ_G0015167	protein coding gene	Chr1:51639500-51663014 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014948	protein coding gene	Chr1:53872759-53894921 (+)
WSB/EiJ	MGP_WSBEiJ_G0015444	protein coding gene	Chr1:53928700-53951851 (+)

Human Ortholog

COQ10B, coenzyme Q10B

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COQ10B, coenzyme Q10B
Links

HGNC:25819

NCBI Gene ID: 80219

neXtProt AC: NX_Q9H8M1

UniProt: Q9H8M1
Chr Location

2q33.1; chr2:197453493-197475310 (+) GRCh38

MGI Vertebrate Homology

Coq10b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: COQ10B
Gene Tree

Coq10b

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Phenotype Summary

10 phenotype references

All Mutations and Alleles

6
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

1
Radiation induced

1
Targeted

2
Genomic Mutations

2 involving Coq10b
Incidental Mutations

APF
Find Mice (IMSR)

21 strains or lines available

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All GO Annotations

5
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

712
Tissues

3
cDNA Data

18
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase coq10b

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All Sequences

65
RefSeq

4
UniProt

3
CCDS

CCDS14959.1, CCDS35568.1

Ensembl

ENSMUSG00000025981 (Evidence)
NCBI Gene

67876

			Length	Strain/Species	Flank
genomic	67876	NCBI Gene Model \| MGI Sequence Detail	19933	C57BL/6J	± kb
transcript	NM_001039710	RefSeq \| MGI Sequence Detail	1748	C57BL/6
polypeptide	Q3THF9	UniProt \| EBI \| MGI Sequence Detail	240	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000005750 coenzyme Q-binding protein COQ10 homolog B, mitochondrial

(term hierarchy)
InterPro Domains

IPR044996 Coenzyme Q-binding protein COQ10-like

IPR005031 Coenzyme Q-binding protein COQ10, START domain

IPR023393 START-like domain superfamily

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All nucleic 21

cDNA 20

Primer pair 1

Microarray probesets 5

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MGI:1921483, MGI:1925811, MGI:2138510, MGI:2138625

Summaries

All 36

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 10
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:305946 Xu M, et al., The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026

TSS for Coq10b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr87	Chr1:55091441-55091452 (+)	-482 bp
Tssr6710	Chr1:55091922-55091936 (+)	0 bp
Tssr6711	Chr1:55091990-55092041 (+)	87 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24