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Atp5mc2 Gene Detail
Summary
  • Symbol
    Atp5mc2
  • Name
    ATP synthase membrane subunit c locus 2
  • Synonyms
    1810041M08Rik, Atp5g2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915192
    NCBI Gene: 67942
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102571303-102579482 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 57.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915192
 protein coding gene Chr15:102571299-102580787 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022422
 protein coding gene Chr15:104871090-104880711 (-)
A/J MGP_AJ_G0022384
 protein coding gene Chr15:100735568-100745072 (-)
AKR/J MGP_AKRJ_G0022359
 protein coding gene Chr15:103791248-103804747 (-)
BALB/cJ MGP_BALBcJ_G0022388
 protein coding gene Chr15:100781396-100790885 (-)
C3H/HeJ MGP_C3HHeJ_G0022155
 protein coding gene Chr15:103861482-103870965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022837
 protein coding gene Chr15:108760882-108770279 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020360
 protein coding gene Chr15:96505940-96515639 (-)
CAST/EiJ MGP_CASTEiJ_G0021681
 protein coding gene Chr15:104729991-104736621 (-)
CBA/J MGP_CBAJ_G0022124
 protein coding gene Chr15:112579285-112588775 (-)
DBA/2J MGP_DBA2J_G0022255
 protein coding gene Chr15:100008897-100019713 (-)
FVB/NJ MGP_FVBNJ_G0022231
 protein coding gene Chr15:99071488-99080998 (-)
LP/J MGP_LPJ_G0022324
 protein coding gene Chr15:105006332-105017137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022253
 protein coding gene Chr15:116122885-116132367 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022849
 protein coding gene Chr15:103830233-103839716 (-)
PWK/PhJ MGP_PWKPhJ_G0021421
 protein coding gene Chr15:100178947-100188613 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021253
 protein coding gene Chr15:103663132-103672685 (-)
WSB/EiJ MGP_WSBEiJ_G0021731
 protein coding gene Chr15:104448205-104457687 (-)



Homology
more
  • Human Ortholog
    ATP5MC2, ATP synthase membrane subunit c locus 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5MC2, ATP synthase membrane subunit c locus 2
  • Synonyms
    ATP5A, ATP5G2
  • Links
    NCBI Gene ID: 517
    neXtProt AC: NX_Q06055
    UniProt: Q06055

  • Chr Location
    12q13.13; chr12:53632726-53681423 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human ATP5MC2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    31 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    803
  • Tissues
    95
  • cDNA Data
    6
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67942 NCBI Gene Model | MGI Sequence Detail 8180 C57BL/6J ±  kb
    transcript NM_026468 RefSeq | MGI Sequence Detail 647 C57BL/6  
    polypeptide P56383 UniProt | EBI | MGI Sequence Detail 146 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000030948 ATP synthase F(0) complex subunit C2, mitochondrial
      (term hierarchy)
    • InterPro Domains
      IPR000454 ATP synthase, F0 complex, subunit C
      IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site
      IPR038662 F1F0 ATP synthase subunit C superfamily
      IPR035921 F/V-ATP synthase subunit C superfamily
      IPR002379 V-ATPase proteolipid subunit C-like domain
    • GlyGen
      P56383 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:7469638
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 31
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory