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Tubb6 Gene Detail
Summary
  • Symbol
    Tubb6
  • Name
    tubulin, beta 6 class V
  • Synonyms
    2310057H16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915201
    NCBI Gene: 67951
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:67523801-67535819 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 39.96 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915201
 protein coding gene Chr18:67523787-67535819 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024523
 protein coding gene Chr18:67677209-67690397 (+)
A/J MGP_AJ_G0024490
 protein coding gene Chr18:64721376-64733819 (+)
AKR/J MGP_AKRJ_G0024460
 protein coding gene Chr18:66619768-66631772 (+)
BALB/cJ MGP_BALBcJ_G0024489
 protein coding gene Chr18:64889068-64901299 (+)
C3H/HeJ MGP_C3HHeJ_G0024257
 protein coding gene Chr18:66774144-66787635 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024936
 protein coding gene Chr18:69467245-69479272 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022367
 protein coding gene Chr18:64096024-64108217 (+)
CAST/EiJ MGP_CASTEiJ_G0023730
 protein coding gene Chr18:66775249-66787235 (+)
CBA/J MGP_CBAJ_G0024227
 protein coding gene Chr18:71866880-71878874 (+)
DBA/2J MGP_DBA2J_G0024357
 protein coding gene Chr18:64372622-64385417 (+)
FVB/NJ MGP_FVBNJ_G0024323
 protein coding gene Chr18:63748261-63760332 (+)
LP/J MGP_LPJ_G0024441
 protein coding gene Chr18:67544457-67556496 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024352
 protein coding gene Chr18:73138439-73150363 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024983
 protein coding gene Chr18:66789700-66803164 (+)
PWK/PhJ MGP_PWKPhJ_G0023473
 protein coding gene Chr18:64651777-64664580 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023279
 protein coding gene Chr18:66953104-66965325 (+)
WSB/EiJ MGP_WSBEiJ_G0023794
 protein coding gene Chr18:66694845-66706578 (+)



Homology
more
  • Human Ortholog
    TUBB6, tubulin beta 6 class V
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBB6, tubulin beta 6 class V
  • Synonyms
    FPVEPD, HsT1601, TUBB-5
  • Links
    NCBI Gene ID: 84617
    neXtProt AC: NX_Q9BUF5
    UniProt: Q9BUF5

  • Chr Location
    18p11.21; chr18:12307669-12344320 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    923
  • Tissues
    40
  • cDNA Data
    121
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67951 NCBI Gene Model | MGI Sequence Detail 12019 C57BL/6J ±  kb
transcript NM_026473 RefSeq | MGI Sequence Detail 1807 FVB/N  
polypeptide Q922F4 UniProt | EBI | MGI Sequence Detail 447 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 123
    cDNA 121
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147390
References
more
  • Summaries
    All 46
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory