Ssxb1 MGI Mouse Gene Detail - MGI:1915235

Ssxb1 Gene Detail

Symbol

Ssxb1
Name

SSX member B1
Synonyms

4930414C09Rik

Feature Type

protein coding gene
IDs

MGI:1915235
NCBI Gene: 67985
Alliance

gene page

Sequence Map

ChrX:8279544-8288396 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 3.81 cM, cytoband A1.1
Mapping Data

3 experiments

SNPs within 2kb

165 from dbSNP Build 142
Strain Annotations

6

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915235	protein coding gene	ChrX:8279544-8288400 (+)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0035525	protein coding gene	ChrX:3579832-3586077 (+)
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0035235	protein coding gene	ChrX:3578541-3586007 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0035201	protein coding gene	ChrX:3847658-3855077 (+)
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0035436	protein coding gene	ChrX:3259144-3306314 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0034660	protein coding gene	ChrX:3312128-3542442 (+)

Human Ortholog

SSX1, SSX family member 1

Vertebrate Orthologs

12

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SSX1, SSX family member 1
Synonyms

CT5.1, SPGFX5, SSRC
Links

HGNC:11335

NCBI Gene ID: 6756

neXtProt AC: NX_Q16384

UniProt: Q16384
Chr Location

Xp11.23; chrX:48255392-48267444 (+) GRCh38

Human Ortholog

SSX2, SSX family member 2
Synonyms

CT5.2, CT5.2A, HD21, HOM-MEL-40, SSX
Links

HGNC:11336

NCBI Gene ID: 6757

neXtProt AC: NX_Q16385

UniProt: Q16385
Chr Location

Xp11.22; chrX:52696896-52707227 (-) GRCh38

Human Ortholog

SSX2B, SSX family member 2B
Synonyms

CT5.2, CT5.2b, HOM-MEL-40, SSX
Links

HGNC:22263

NCBI Gene ID: 727837

neXtProt AC: NX_Q16385

UniProt: Q16385
Chr Location

Xp11.22; chrX:52751132-52790305 (+) GRCh38

Human Ortholog

SSX3, SSX family member 3
Synonyms

CT5.3
Links

HGNC:11337

NCBI Gene ID: 10214

neXtProt AC: NX_Q99909

UniProt: Q99909
Chr Location

Xp11.23; chrX:48346427-48356707 (-) GRCh38

Human Ortholog

SSX4, SSX family member 4
Synonyms

CT5.4
Links

HGNC:11338

NCBI Gene ID: 6759

neXtProt AC: NX_O60224

UniProt: O60224
Chr Location

Xp11.23

Human Ortholog

SSX4B, SSX family member 4B
Synonyms

CT5.4
Links

HGNC:16880

NCBI Gene ID: 548313

neXtProt AC: NX_O60224

UniProt: O60224
Chr Location

Xp11.23

Human Ortholog

SSX5, SSX family member 5
Links

HGNC:11339

NCBI Gene ID: 6758

neXtProt AC: NX_O60225

UniProt: O60225
Chr Location

Xp11.23; chrX:48186220-48196795 (-) GRCh38

Human Ortholog

SSX6P, SSX family member 6, pseudogene
Synonyms

dJ54B20.1, psiSSX2, SSX6, SSXP2
Links

HGNC:19652

NCBI Gene ID: 280657

UniProt: Q7RTT6
Chr Location

Xp11.23; chrX:48107982-48120686 (+) GRCh38

Human Ortholog

SSX7, SSX family member 7
Links

HGNC:19653

NCBI Gene ID: 280658

neXtProt AC: NX_Q7RTT5

UniProt: Q7RTT5
Chr Location

Xp11.22; chrX:52644061-52654900 (-) GRCh38

Human Ortholog

SSX8P, SSX family member 8, pseudogene
Synonyms

SSX8
Links

HGNC:19654

NCBI Gene ID: 280659

UniProt: Q7RTT4
Chr Location

Xp11.22; chrX:52622935-52633948 (+) GRCh38

Human Ortholog

SSX9P, SSX family member 9, pseudogene
Synonyms

SSX9
Links

HGNC:19655

NCBI Gene ID: 280660

UniProt: Q7RTT3
Chr Location

Xp11.23; chrX:48296816-48306179 (-) GRCh38

MGI Vertebrate Homology

Ssxb1 stringent orthology
11 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SSX1, SSX2, SSX2B, SSX3, SSX4, SSX4B, SSX5, SSX6P, SSX7, SSX8P, SSX9P
Gene Tree

Ssxb1

Diseases

2 with human SSX1,SSX2 associations

				Human Disease	Mouse Models
				synovial sarcoma IDs synovial sarcoma DOID:5485 MESH:D013584 NCI:C3400 OMIM:300813 UMLS_CUI:C0039101
				X-linked spermatogenic failure 5 IDs X-linked spermatogenic failure 5 DOID:0070596 OMIM:301099

Click on a disease name to see all genes associated with that disease.

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All GO Annotations

3
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

4
UniProt

2
CCDS

CCDS29997.1

Ensembl

ENSMUSG00000079705 (Evidence)
NCBI Gene

67985

			Length	Strain/Species	Flank
genomic	ENSMUSG00000079705	Ensembl Gene Model \| MGI Sequence Detail	8853	C57BL/6J	± kb
transcript	ENSMUST00000037297	Ensembl \| MGI Sequence Detail	875	Not Applicable
polypeptide	ENSMUSP00000037624	Ensembl \| MGI Sequence Detail	170	Not Applicable

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UniProt

2 Sequences
InterPro Domains

IPR003655 Ancestral KRAB domain

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR019041 SSXRD motif

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All nucleic 4

cDNA 4

Microarray probesets 3

Summaries

All 14

Gene Ontology 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:86525 Chen YT, et al., Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression. Genomics. 2003 Dec;82(6):628-36

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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