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Naa10 Gene Detail
Summary
  • Symbol
    Naa10
  • Name
    N(alpha)-acetyltransferase 10, NatA catalytic subunit
  • Synonyms
    2310039H09Rik, Ard1, Ard1a, Te2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915255
    NCBI Gene: 56292
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72960479-72965550 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915255
 protein coding gene ChrX:72960476-72965550 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035826
 protein coding gene ChrX:69698439-69704113 (-)
A/J MGP_AJ_G0035807
 protein coding gene ChrX:69892930-69899634 (-)
AKR/J MGP_AKRJ_G0035732
 protein coding gene ChrX:71738251-71743312 (-)
BALB/cJ MGP_BALBcJ_G0035792
 protein coding gene ChrX:68920889-68925910 (-)
C3H/HeJ MGP_C3HHeJ_G0035497
 protein coding gene ChrX:70174735-70179831 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036322
 protein coding gene ChrX:71841382-71847224 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033166
 protein coding gene ChrX:68924463-68929565 (-)
CAST/EiJ MGP_CASTEiJ_G0034788
 protein coding gene ChrX:55523759-55530325 (-)
CBA/J MGP_CBAJ_G0035472
 protein coding gene ChrX:73838227-73843297 (-)
DBA/2J MGP_DBA2J_G0035629
 protein coding gene ChrX:69349561-69354595 (-)
FVB/NJ MGP_FVBNJ_G0035573
 protein coding gene ChrX:68685104-68690396 (-)
LP/J MGP_LPJ_G0035714
 protein coding gene ChrX:70480047-70485128 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035611
 protein coding gene ChrX:76390229-76395296 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036344
 protein coding gene ChrX:69521193-69526261 (-)
PWK/PhJ MGP_PWKPhJ_G0034487
 protein coding gene ChrX:53532369-53537426 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034321
 protein coding gene ChrX:56421030-56426121 (-)
WSB/EiJ MGP_WSBEiJ_G0034929
 protein coding gene ChrX:68792746-68797806 (-)



Homology
more
  • Human Ortholog
    NAA10, N-alpha-acetyltransferase 10, NatA catalytic subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NAA10, N-alpha-acetyltransferase 10, NatA catalytic subunit
  • Synonyms
    ARD1, ARD1A, ARD1P, DXS707, hARD1, LZMS, MAA, MCOPS1, NATD, OGDNS, TE2
  • Links
    NCBI Gene ID: 8260
    neXtProt AC: NX_P41227
    UniProt: P41227

  • Chr Location
    Xq28; chrX:153929225-153935080 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human NAA10 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    47 phenotypes from 4 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased bone development with increased osteoblast activity, increased bone density, and increased bone thickness of calvaria.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    8
  • cDNA Data
    101
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031388 Ensembl Gene Model | MGI Sequence Detail 5072 C57BL/6J ±  kb
    transcript ENSMUST00000033763 Ensembl | MGI Sequence Detail 962 Not Applicable  
    polypeptide ENSMUSP00000033763 Ensembl | MGI Sequence Detail 235 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 107
      cDNA 105
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 5
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:349445 Lyon GJ, et al., Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice. PLoS One. 2024;19(5):e0301328
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory