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Zdhhc15 Gene Detail
Summary
  • Symbol
    Zdhhc15
  • Name
    zinc finger, DHHC domain containing 15
  • Synonyms
    6030457O13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915336
    NCBI Gene: 108672
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:103580575-103714670 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 46.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2014 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915336
 protein coding gene ChrX:103580575-103714696 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035992
 protein coding gene ChrX:101260315-101399762 (-)
A/J MGP_AJ_G0035973
 protein coding gene ChrX:101121413-101258680 (-)
AKR/J MGP_AKRJ_G0035891
 protein coding gene ChrX:104239414-104389262 (-)
BALB/cJ MGP_BALBcJ_G0035963
 protein coding gene ChrX:99921883-100053059 (-)
C3H/HeJ MGP_C3HHeJ_G0035669
 protein coding gene ChrX:101711916-101850649 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036489
 protein coding gene ChrX:104207300-104339326 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033317
 protein coding gene ChrX:98712848-98830474 (-)
CAST/EiJ MGP_CASTEiJ_G0034955
 protein coding gene ChrX:85958300-86095967 (-)
CBA/J MGP_CBAJ_G0035644
 protein coding gene ChrX:107439739-107596444 (-)
DBA/2J MGP_DBA2J_G0035798
 protein coding gene ChrX:100378931-100522775 (-)
FVB/NJ MGP_FVBNJ_G0035739
 protein coding gene ChrX:99687999-99824689 (-)
LP/J MGP_LPJ_G0035891
 protein coding gene ChrX:102238986-102373445 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035771
 protein coding gene ChrX:112131290-112280520 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036515
 protein coding gene ChrX:100921150-101059919 (-)
PWK/PhJ MGP_PWKPhJ_G0034653
 protein coding gene ChrX:83515987-83645142 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034481
 protein coding gene ChrX:86680771-86814814 (-)
WSB/EiJ MGP_WSBEiJ_G0035095
 protein coding gene ChrX:99645645-99777778 (-)



Homology
more
  • Human Ortholog
    ZDHHC15, zinc finger DHHC-type palmitoyltransferase 15
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDHHC15, zinc finger DHHC-type palmitoyltransferase 15
  • Synonyms
    DHHC15, MRX91
  • Links
    NCBI Gene ID: 158866
    neXtProt AC: NX_Q96MV8
    UniProt: Q96MV8

  • Chr Location
    Xq13.3; chrX:75368427-75523502 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 images
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male chimeras hemizygous for a gene trapped allele exhibit a severe developmental delay and neural tube defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    97
  • cDNA Data
    29
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033906 Ensembl Gene Model | MGI Sequence Detail 134096 C57BL/6J ±  kb
    transcript ENSMUST00000042070 Ensembl | MGI Sequence Detail 5509 Not Applicable  
    polypeptide ENSMUSP00000047615 Ensembl | MGI Sequence Detail 337 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 29
      Primer pair 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:287027 Greaves J, et al., Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1365-E1374
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory