About   Help   FAQ
Etaa1 Gene Detail
Summary
  • Symbol
    Etaa1
  • Name
    Ewing tumor-associated antigen 1
  • Synonyms
    5730466H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915395
    NCBI Gene: 68145
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:17888756-17903875 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 10.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    557 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915395
 protein coding gene Chr11:17888753-17903875 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018060
 protein coding gene Chr11:15369183-15383937 (-)
A/J MGP_AJ_G0018033
 protein coding gene Chr11:14855434-14870188 (-)
AKR/J MGP_AKRJ_G0017997
 protein coding gene Chr11:15373935-15388783 (-)
BALB/cJ MGP_BALBcJ_G0018001
 protein coding gene Chr11:14975397-14990151 (-)
C3H/HeJ MGP_C3HHeJ_G0017815
 protein coding gene Chr11:15319706-15334460 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018453
 protein coding gene Chr11:16021037-16037063 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016111
 protein coding gene Chr11:13985739-13999327 (-)
CAST/EiJ MGP_CASTEiJ_G0017376
 protein coding gene Chr11:15282242-15290458 (-)
CBA/J MGP_CBAJ_G0017789
 protein coding gene Chr11:16838276-16852825 (-)
DBA/2J MGP_DBA2J_G0017899
 protein coding gene Chr11:14844028-14858808 (-)
FVB/NJ MGP_FVBNJ_G0017891
 protein coding gene Chr11:14616867-14631620 (-)
LP/J MGP_LPJ_G0017970
 protein coding gene Chr11:15515093-15530206 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017917
 protein coding gene Chr11:17291194-17305036 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018494
 protein coding gene Chr11:15470097-15484854 (-)
PWK/PhJ MGP_PWKPhJ_G0017156
 protein coding gene Chr11:14802648-14816174 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016953
 protein coding gene Chr11:15212467-15224328 (-)
WSB/EiJ MGP_WSBEiJ_G0017430
 protein coding gene Chr11:15142619-15165200 (-)



Homology
more
  • Human Ortholog
    ETAA1, ETAA1 activator of ATR kinase
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ETAA1, ETAA1 activator of ATR kinase
  • Synonyms
    ETAA16
  • Links
    NCBI Gene ID: 54465
    neXtProt AC: NX_Q9NY74
    UniProt: Q9NY74

  • Chr Location
    2p14; chr2:67397322-67412089 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (ENU)
    2
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Targeted
    2
  • Genomic Mutations
    1 involving Etaa1
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    46 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    34
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016984 Ensembl Gene Model | MGI Sequence Detail 15120 C57BL/6J ±  kb
transcript ENSMUST00000076661 Ensembl | MGI Sequence Detail 4185 Not Applicable  
polypeptide ENSMUSP00000075957 Ensembl | MGI Sequence Detail 877 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144038
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:244584 Miosge LA, et al., Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5216-E5225
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory