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Tmem86b Gene Detail
Summary
  • Symbol
    Tmem86b
  • Name
    transmembrane protein 86B
  • Synonyms
    C330014O21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915505
    NCBI Gene: 68255
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4631039-4634211 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    148 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915505
 protein coding gene Chr7:4631039-4634421 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031552
 protein coding gene Chr7:1547919-1551301 (-)
A/J MGP_AJ_G0031526
 protein coding gene Chr7:1561069-1564451 (-)
AKR/J MGP_AKRJ_G0031455
 protein coding gene Chr7:1622691-1626073 (-)
BALB/cJ MGP_BALBcJ_G0031534
 protein coding gene Chr7:1604185-1607567 (-)
C3H/HeJ MGP_C3HHeJ_G0031255
 protein coding gene Chr7:1598249-1601631 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031995
 protein coding gene Chr7:1606240-1609622 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029119
 protein coding gene Chr7:1312808-1315991 (-)
CAST/EiJ MGP_CASTEiJ_G0030619
 protein coding gene Chr7:1535750-1539147 (-)
CBA/J MGP_CBAJ_G0031213
 protein coding gene Chr7:1793875-1797257 (-)
DBA/2J MGP_DBA2J_G0031372
 protein coding gene Chr7:1537554-1540936 (-)
FVB/NJ MGP_FVBNJ_G0031324
 protein coding gene Chr7:1507342-1510724 (-)
LP/J MGP_LPJ_G0031457
 protein coding gene Chr7:1660967-1665181 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031363
 protein coding gene Chr7:1730355-1734549 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032025
 protein coding gene Chr7:1532698-1536080 (-)
PWK/PhJ MGP_PWKPhJ_G0030347
 protein coding gene Chr7:1707758-1711201 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030172
 protein coding gene Chr7:1587195-1590585 (-)
WSB/EiJ MGP_WSBEiJ_G0030714
 protein coding gene Chr7:1547901-1551283 (-)



Homology
more
  • Human Ortholog
    TMEM86B, transmembrane protein 86B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM86B, transmembrane protein 86B
  • Links
    NCBI Gene ID: 255043
    neXtProt AC: NX_Q8N661
    UniProt: Q8N661

  • Chr Location
    19q13.42; chr19:55226638-55228784 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    13
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68255 NCBI Gene Model | MGI Sequence Detail 3173 C57BL/6J ±  kb
transcript NM_023440 RefSeq | MGI Sequence Detail 1222 C57BL/6  
polypeptide Q497J1 UniProt | EBI | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory