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Nufip2 Gene Detail
Summary
  • Symbol
    Nufip2
  • Name
    nuclear FMR1 interacting protein 2
  • Synonyms
    1110001M19Rik, 9530056D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915814
    NCBI Gene: 68564
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:77576566-77608792 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    565 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915814
protein coding gene Chr11:77576566-77632747 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018753
protein coding gene Chr11:78623817-78689641 (+)
A/J MGP_AJ_G0018719
protein coding gene Chr11:75636268-75692487 (+)
AKR/J MGP_AKRJ_G0018689
protein coding gene Chr11:77933312-77992551 (+)
BALB/cJ MGP_BALBcJ_G0018693
protein coding gene Chr11:76031288-76088790 (+)
C3H/HeJ MGP_C3HHeJ_G0018506
protein coding gene Chr11:77963805-78027820 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019144
protein coding gene Chr11:81093268-81157379 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016779
protein coding gene Chr11:72609940-72640189 (+)
CAST/EiJ MGP_CASTEiJ_G0018060
protein coding gene Chr11:78381065-78437314 (+)
CBA/J MGP_CBAJ_G0018476
protein coding gene Chr11:84622784-84688652 (+)
DBA/2J MGP_DBA2J_G0018585
protein coding gene Chr11:75222065-75278887 (+)
FVB/NJ MGP_FVBNJ_G0018575
protein coding gene Chr11:74801447-74859083 (+)
LP/J MGP_LPJ_G0018656
protein coding gene Chr11:79176774-79238788 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018601
protein coding gene Chr11:85071627-85135814 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019184
protein coding gene Chr11:78155823-78222213 (+)
PWK/PhJ MGP_PWKPhJ_G0017831
protein coding gene Chr11:75981947-76046491 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017622
protein coding gene Chr11:77760937-77786242 (+)
WSB/EiJ MGP_WSBEiJ_G0018113
protein coding gene Chr11:77975901-78038429 (+)



Homology
more
  • Human Ortholog
    NUFIP2, nuclear FMR1 interacting protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUFIP2, nuclear FMR1 interacting protein 2
  • Synonyms
    182-FIP, 82-FIP, FIP-82, NUFP2, PIG1
  • Links
    NCBI Gene ID: 57532
    neXtProt AC: NX_Q7Z417
    UniProt: Q7Z417

  • Chr Location
    17q11.2; chr17:29255839-29294148 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68564 NCBI Gene Model | MGI Sequence Detail 32227 C57BL/6J ±  kb
    transcript NM_001024205 RefSeq | MGI Sequence Detail 10399 C57BL/6  
    polypeptide Q5F2E7 UniProt | EBI | MGI Sequence Detail 692 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000011502 FMR1-interacting protein NUFIP2
    • InterPro Domains
      IPR032747 FMR1-interacting protein 2
    • GlyGen
      Q5F2E7 7 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (5 sites)
    Molecular
    Reagents
    less
    • All nucleic 81
      cDNA 81

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1925921, MGI:2144097, MGI:2144180
    References
    more
    • Summaries
      All 48
      Gene Ontology 5
      Phenotypes 20
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory