Gask1b Gene Detail

Summary

• Symbol
  Gask1b
• Name
  golgi associated kinase 1B
• Synonyms
  1110032E23Rik, 2210419I08Rik, Ened, Fam198b

• Feature Type
  protein coding gene
• IDs
  MGI:1915909
  NCBI Gene: 68659
• Alliance
  gene page
• Transcription Start Sites
  17 TSS

Location &
Maps

• Sequence Map
  Chr3:79791840-79853587 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 35.13 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  2068 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915909	protein coding gene	Chr3:79791795-79853587 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027318	protein coding gene	Chr3:79600999-79664212 (+)
A/J	MGP_AJ_G0027280	protein coding gene	Chr3:76987959-77050952 (+)
AKR/J	MGP_AKRJ_G0027248	protein coding gene	Chr3:78758369-78820798 (+)
BALB/cJ	MGP_BALBcJ_G0027291	protein coding gene	Chr3:77023616-77086882 (+)
C3H/HeJ	MGP_C3HHeJ_G0027035	protein coding gene	Chr3:79095724-79159754 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027737	protein coding gene	Chr3:82643647-82709665 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025090	protein coding gene	Chr3:72915351-72975865 (+)
CAST/EiJ	MGP_CASTEiJ_G0026482	protein coding gene	Chr3:79168966-79232180 (+)
CBA/J	MGP_CBAJ_G0027010	protein coding gene	Chr3:85360162-85427231 (+)
DBA/2J	MGP_DBA2J_G0027146	protein coding gene	Chr3:76554641-76616517 (+)
FVB/NJ	MGP_FVBNJ_G0027114	protein coding gene	Chr3:74886043-74947058 (+)
LP/J	MGP_LPJ_G0027254	protein coding gene	Chr3:80566250-80629432 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027133	protein coding gene	Chr3:91615987-91684002 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027795	protein coding gene	Chr3:78599290-78663871 (+)
PWK/PhJ	MGP_PWKPhJ_G0026216	protein coding gene	Chr3:76306994-76369247 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026032	protein coding gene	Chr3:77759280-77830093 (+)
WSB/EiJ	MGP_WSBEiJ_G0026560	protein coding gene	Chr3:78942084-79005785 (+)

Homology

• Human Ortholog
  GASK1B, golgi associated kinase 1B

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  GASK1B, golgi associated kinase 1B
  
• Synonyms
  AD021, AD036, C4orf18, ENED, FAM198B
• Links
  HGNC:25312

  NCBI Gene ID: 51313

  neXtProt AC: NX_Q6UWH4

  UniProt: Q6UWH4

  
  
• Chr Location
  4q32.1; chr4:158124474-158173318 (-)  GRCh38

---

• MGI Vertebrate Homology
  Gask1b stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: GASK1B
• Gene Tree
  Gask1b
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Gask1b
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  27 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  3

Expression

• Assay Results
  837
• Tissues
  50
• cDNA Data
  13
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase gask1b

Sequences &
Gene Models

• All Sequences
  53
• RefSeq
  6
• UniProt
  2
• CCDS
  CCDS17422.1

• Ensembl
  ENSMUSG00000027955 (Evidence)
• NCBI Gene
  68659

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000027955	Ensembl Gene Model | MGI Sequence Detail	61748	C57BL/6J
transcript	ENSMUST00000118853	Ensembl | MGI Sequence Detail	6729	Not Applicable
polypeptide	ENSMUSP00000114093	Ensembl | MGI Sequence Detail	517	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000032287 Golgi-associated kinase 1B
  (term hierarchy)
• InterPro Domains
  IPR029207 FAM198 family
• GlyGen
  Q3UPI1 2 sites

Molecular
Reagents

• All nucleic 13

  cDNA 13

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1920913, MGI:2139925, MGI:6276587

References

• Summaries
  All 32

  Developmental Gene Expression 3

  Diseases 1

  Gene Ontology 3

  Phenotypes 7
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Gask1b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr29596	Chr3:79791803-79791878 (+)	1 bp
Tssr29597	Chr3:79791883-79791899 (+)	51 bp
Tssr29598	Chr3:79792331-79792397 (+)	524 bp
Tssr29599	Chr3:79792413-79792426 (+)	580 bp
Tssr29600	Chr3:79792459-79792475 (+)	627 bp
Tssr29601	Chr3:79792490-79792504 (+)	657 bp
Tssr29602	Chr3:79793256-79793309 (+)	1,443 bp
Tssr29603	Chr3:79793347-79793371 (+)	1,519 bp
Tssr29604	Chr3:79793419-79793428 (+)	1,584 bp
Tssr29605	Chr3:79793488-79793516 (+)	1,662 bp
Tssr29606	Chr3:79793521-79793534 (+)	1,688 bp
Tssr29607	Chr3:79794191-79794202 (+)	2,357 bp
Tssr29608	Chr3:79794209-79794262 (+)	2,396 bp
Tssr29609	Chr3:79807985-79807989 (+)	16,147 bp
Tssr29610	Chr3:79815953-79815964 (+)	24,119 bp
Tssr29611	Chr3:79843744-79843753 (+)	51,909 bp
Tssr29612	Chr3:79843771-79843777 (+)	51,934 bp