Lce1e MGI Mouse Gene Detail - MGI:1915944 - late cornified envelope 1E

Symbol

Lce1e
Name

late cornified envelope 1E
Synonyms

1110031B11Rik

Feature Type

protein coding gene
IDs

MGI:1915944
NCBI Gene: 68694
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr3:92614708-92616381 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 40.14 cM
Mapping Data

1 experiment

SNPs within 2kb

183 from dbSNP Build 142
Strain Annotations

14

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915944	protein coding gene	Chr3:92614707-92616381 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027511	protein coding gene	Chr3:93161788-93163461 (-)
A/J	MGP_AJ_G0027478	protein coding gene	Chr3:90230877-90232668 (-)
AKR/J	MGP_AKRJ_G0027443	protein coding gene	Chr3:92341525-92343198 (-)
BALB/cJ	MGP_BALBcJ_G0027486	protein coding gene	Chr3:90038498-90040606 (-)
C3H/HeJ	MGP_C3HHeJ_G0027226	protein coding gene	Chr3:92564186-92565859 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027930	protein coding gene	Chr3:96703923-96705596 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0027200	protein coding gene	Chr3:100032217-100034350 (-)
DBA/2J	MGP_DBA2J_G0027338	protein coding gene	Chr3:89558741-89560414 (-)
FVB/NJ	MGP_FVBNJ_G0027306	protein coding gene	Chr3:87722275-87723918 (-)
LP/J	MGP_LPJ_G0027446	protein coding gene	Chr3:94377302-94378945 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027331	protein coding gene	Chr3:106311608-106313735 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027989	protein coding gene	Chr3:92075450-92077123 (-)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0026225	protein coding gene	Chr3:90424756-90425343 (-)
WSB/EiJ	no annotation

Human Ortholog

LCE2A, late cornified envelope 2A

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

LCE2A, late cornified envelope 2A
Synonyms

LEP9
Links

HGNC:29469

NCBI Gene ID: 353139

neXtProt AC: NX_Q5TA79

UniProt: Q5TA79
Chr Location

1q21.3; chr1:152698345-152699442 (+) GRCh38

Human Ortholog

LCE2C, late cornified envelope 2C
Synonyms

LEP11
Links

HGNC:29460

NCBI Gene ID: 353140

neXtProt AC: NX_Q5TA81

UniProt: Q5TA81
Chr Location

1q21.3; chr1:152675279-152676569 (+) GRCh38

Human Ortholog

LCE2D, late cornified envelope 2D
Synonyms

LEP12, SPRL1A
Links

HGNC:16518

NCBI Gene ID: 353141

neXtProt AC: NX_Q5TA82

UniProt: Q5TA82
Chr Location

1q21.3

Human Ortholog

LCE5A, late cornified envelope 5A
Synonyms

LEP18, SPRL5A
Links

HGNC:16614

NCBI Gene ID: 254910

neXtProt AC: NX_Q5TCM9

UniProt: Q5TCM9
Chr Location

1q21.3; chr1:152510803-152512177 (+) GRCh38

MGI Vertebrate Homology

Lce1e stringent orthology
4 human;1 mouse
HCOP

vertebrate homology predictions: LCE2A, LCE2C, LCE2D, LCE5A
Gene Tree

Lce1e

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References

1 with disease annotations

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Radiation induced

1
Genomic Mutations

2 involving Lce1e
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

5

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

26
RefSeq

2
UniProt

1
CCDS

CCDS17567.1

Ensembl

ENSMUSG00000068889 (Evidence)
NCBI Gene

68694

			Length	Strain/Species	Flank
genomic	ENSMUSG00000068889	Ensembl Gene Model \| MGI Sequence Detail	1674	C57BL/6J	± kb
transcript	ENSMUST00000090867	Ensembl \| MGI Sequence Detail	711	Not Applicable
polypeptide	ENSMUSP00000088380	Ensembl \| MGI Sequence Detail	143	Not Applicable

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UniProt

1 Sequence

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All nucleic 5

cDNA 5

Microarray probesets 2

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MGI:2139748

Summaries

All 19

Diseases 1

Gene Ontology 1

Phenotypes 4
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Lce1e:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34328	Chr3:92616380-92616382 (-)	0 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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