About   Help   FAQ
Btbd10 Gene Detail
Summary
  • Symbol
    Btbd10
  • Name
    BTB domain containing 10
  • Synonyms
    1110056N09Rik, Gmrp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916065
    NCBI Gene: 68815
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:112914833-112968599 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 59.18 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    968 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916065
 protein coding gene Chr7:112914833-112970734 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032874
 protein coding gene Chr7:116955118-117009421 (-)
A/J MGP_AJ_G0032857
 protein coding gene Chr7:114006131-114059764 (-)
AKR/J MGP_AKRJ_G0032789
 protein coding gene Chr7:116879324-116935867 (-)
BALB/cJ MGP_BALBcJ_G0032862
 protein coding gene Chr7:113712974-113766631 (-)
C3H/HeJ MGP_C3HHeJ_G0032572
 protein coding gene Chr7:116878042-116932878 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033368
 protein coding gene Chr7:121687092-121739980 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030340
 protein coding gene Chr7:115586165-115641875 (-)
CAST/EiJ MGP_CASTEiJ_G0031900
 protein coding gene Chr7:108503751-108561876 (-)
CBA/J MGP_CBAJ_G0032545
 protein coding gene Chr7:125715340-125780376 (-)
DBA/2J MGP_DBA2J_G0032697
 protein coding gene Chr7:112085473-112140043 (-)
FVB/NJ MGP_FVBNJ_G0032650
 protein coding gene Chr7:111942168-111995852 (-)
LP/J MGP_LPJ_G0032791
 protein coding gene Chr7:118454926-118511856 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032682
 protein coding gene Chr7:127291242-127367440 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033388
 protein coding gene Chr7:115878763-115932733 (-)
PWK/PhJ MGP_PWKPhJ_G0031607
 protein coding gene Chr7:104935904-104989903 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031455
 protein coding gene Chr7:102657857-102707157 (-)
WSB/EiJ MGP_WSBEiJ_G0032013
 protein coding gene Chr7:116755167-116810012 (-)



Homology
more
  • Human Ortholog
    BTBD10, BTB domain containing 10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BTBD10, BTB domain containing 10
  • Synonyms
    GMRP-1, GMRP1
  • Links
    NCBI Gene ID: 84280
    neXtProt AC: NX_Q9BSF8
    UniProt: Q9BSF8

  • Chr Location
    11p15.3; chr11:13388008-13463297 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038187 Ensembl Gene Model | MGI Sequence Detail 53767 C57BL/6J ±  kb
transcript ENSMUST00000117577 Ensembl | MGI Sequence Detail 2384 Not Applicable  
polypeptide ENSMUSP00000113496 Ensembl | MGI Sequence Detail 483 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 43
    Gene Ontology 4
    Phenotypes 19
  • Earliest
    J:61682 Hagiwara N, et al., Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4180-5
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory