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Fcsk Gene Detail
Summary
  • Symbol
    Fcsk
  • Name
    fucose kinase
  • Synonyms
    1110046B12Rik, Fuk, L-fucose kinase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916071
    NCBI Gene: 234730
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:111609088-111629120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 57.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    608 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916071
 protein coding gene Chr8:111609088-111629120 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034130
 protein coding gene Chr8:113574170-113598782 (-)
A/J MGP_AJ_G0034109
 protein coding gene Chr8:108985469-109006246 (-)
AKR/J MGP_AKRJ_G0034036
 protein coding gene Chr8:112168702-112190178 (-)
BALB/cJ MGP_BALBcJ_G0034103
 protein coding gene Chr8:109165530-109185389 (-)
C3H/HeJ MGP_C3HHeJ_G0033814
 protein coding gene Chr8:112883897-112905975 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034623
 protein coding gene Chr8:117570118-117591408 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031565
 protein coding gene Chr8:101968674-101989648 (-)
CAST/EiJ MGP_CASTEiJ_G0033141
 protein coding gene Chr8:112502076-112524148 (-)
CBA/J MGP_CBAJ_G0033788
 protein coding gene Chr8:121561154-121584238 (-)
DBA/2J MGP_DBA2J_G0033943
 protein coding gene Chr8:108277377-108297852 (-)
FVB/NJ MGP_FVBNJ_G0033887
 protein coding gene Chr8:107234254-107255198 (-)
LP/J MGP_LPJ_G0034033
 protein coding gene Chr8:113765763-113786800 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033933
 protein coding gene Chr8:124470390-124494100 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034642
 protein coding gene Chr8:112137663-112158270 (-)
PWK/PhJ MGP_PWKPhJ_G0032844
 protein coding gene Chr8:107858852-107879171 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032683
 protein coding gene Chr8:110824601-110846629 (-)
WSB/EiJ MGP_WSBEiJ_G0033257
 protein coding gene Chr8:112825744-112846927 (-)



Homology
more
  • Human Ortholog
    FCSK, fucose kinase
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FCSK, fucose kinase
  • Synonyms
    1110046B12Rik, CDGF2, FUK
  • Links
    NCBI Gene ID: 197258
    neXtProt AC: NX_Q8N0W3
    UniProt: Q8N0W3

  • Chr Location
    16q22.1; chr16:70454595-70480274 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    35
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234730 NCBI Gene Model | MGI Sequence Detail 20033 C57BL/6J ±  kb
transcript NR_052009 RefSeq | MGI Sequence Detail 3972 C57BL/6  
polypeptide Q7TMC8 UniProt | EBI | MGI Sequence Detail 1090 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 35
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142493, MGI:6286359
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory