Slx9 MGI Mouse Gene Detail - MGI:1916334 - SLX9 ribosome biogenesis factor

Symbol

Slx9
Name

SLX9 ribosome biogenesis factor
Synonyms

1810008A18Rik, Fam207a

Feature Type

protein coding gene
IDs

MGI:1916334
NCBI Gene: 108707
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr10:77322495-77351619 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 39.72 cM
Mapping Data

2 experiments

SNPs within 2kb

806 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916334	protein coding gene	Chr10:77322489-77352758 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017397	protein coding gene	Chr10:77804698-77835714 (-)
A/J	MGP_AJ_G0017374	protein coding gene	Chr10:75106281-75135116 (-)
AKR/J	MGP_AKRJ_G0017335	protein coding gene	Chr10:77110417-77140396 (-)
BALB/cJ	MGP_BALBcJ_G0017334	protein coding gene	Chr10:75300811-75330555 (-)
C3H/HeJ	MGP_C3HHeJ_G0017158	protein coding gene	Chr10:77194409-77226086 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017792	protein coding gene	Chr10:80524936-80564198 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015482	protein coding gene	Chr10:71534893-71566731 (-)
CAST/EiJ	MGP_CASTEiJ_G0016728	protein coding gene	Chr10:77538966-77574007 (-)
CBA/J	MGP_CBAJ_G0017130	protein coding gene	Chr10:83655789-83686367 (-)
DBA/2J	MGP_DBA2J_G0017235	protein coding gene	Chr10:74386743-74415370 (-)
FVB/NJ	MGP_FVBNJ_G0017227	protein coding gene	Chr10:73558839-73587715 (-)
LP/J	MGP_LPJ_G0017308	protein coding gene	Chr10:78277891-78311286 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017256	protein coding gene	Chr10:85687109-85719693 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017831	protein coding gene	Chr10:77187535-77220136 (-)
PWK/PhJ	MGP_PWKPhJ_G0016512	protein coding gene	Chr10:74259886-74293695 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0016295	protein coding gene	Chr10:76454796-76483154 (-)
WSB/EiJ	MGP_WSBEiJ_G0016791	protein coding gene	Chr10:77166480-77195700 (-)

Human Ortholog

SLX9, SLX9 ribosome biogenesis factor

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLX9, SLX9 ribosome biogenesis factor
Synonyms

C21orf70, FAM207A, PRED56
Links

HGNC:15811

NCBI Gene ID: 85395

neXtProt AC: NX_Q9NSI2

UniProt: Q9NSI2
Chr Location

21q22.3; chr21:44939697-44976973 (+) GRCh38

MGI Vertebrate Homology

Slx9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLX9
Gene Tree

Slx9

less

References

2 with disease annotations

less

Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
40 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

17
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

7
Targeted

7
Genomic Mutations

4 involving Slx9
Find Mice (IMSR)

21 strains or lines available

less

All GO Annotations

4
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

772
Tissues

65
cDNA Data

10
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slx9

less

All Sequences

49
RefSeq

4
UniProt

4
CCDS

CCDS23955.1

Ensembl

ENSMUSG00000032977 (Evidence)
NCBI Gene

108707

			Length	Strain/Species	Flank
genomic	ENSMUSG00000032977	Ensembl Gene Model \| MGI Sequence Detail	29125	C57BL/6J	± kb
transcript	ENSMUST00000045454	Ensembl \| MGI Sequence Detail	2394	Not Applicable
polypeptide	ENSMUSP00000036382	Ensembl \| MGI Sequence Detail	219	Not Applicable

less

UniProt

4 Sequences
Protein Ontology

PR:000032186 ribosome biogenesis protein SLX9 homolog

(term hierarchy)
InterPro Domains

IPR028160 Ribosome biogenesis protein Slx9-like

less

All nucleic 12

cDNA 10

Primer pair 2

Microarray probesets 5

less

MGI:2143559, MGI:7469432

Summaries

All 64

Developmental Gene Expression 2

Diseases 2

Gene Ontology 2

Phenotypes 40
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slx9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr3260	Chr10:77351653-77351660 (-)	-38 bp
Tssr98236	Chr10:77351609-77351652 (-)	-12 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24