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Rhebl1 Gene Detail
Summary
  • Symbol
    Rhebl1
  • Name
    Ras homolog enriched in brain like 1
  • Synonyms
    1810036J22Rik, Rheb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916409
    NCBI Gene: 69159
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98775659-98779424 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 54.99 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916409
 protein coding gene Chr15:98775659-98792421 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022315
 protein coding gene Chr15:100641250-100644878 (-)
A/J MGP_AJ_G0022273
 protein coding gene Chr15:96667462-96671089 (-)
AKR/J MGP_AKRJ_G0022248
 protein coding gene Chr15:99643063-99646690 (-)
BALB/cJ MGP_BALBcJ_G0022280
 protein coding gene Chr15:96862990-96866613 (-)
C3H/HeJ MGP_C3HHeJ_G0022048
 protein coding gene Chr15:99693994-99697621 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022725
 protein coding gene Chr15:104388130-104391797 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020250
 protein coding gene Chr15:92583669-92587528 (-)
CAST/EiJ MGP_CASTEiJ_G0021571
 protein coding gene Chr15:100545792-100549405 (-)
CBA/J MGP_CBAJ_G0022017
 protein coding gene Chr15:107930037-107933664 (-)
DBA/2J MGP_DBA2J_G0022143
 protein coding gene Chr15:96115421-96119049 (-)
FVB/NJ MGP_FVBNJ_G0022123
 protein coding gene Chr15:95090965-95094593 (-)
LP/J MGP_LPJ_G0022215
 protein coding gene Chr15:100792608-100796236 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022143
 protein coding gene Chr15:111923730-111927403 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022740
 protein coding gene Chr15:99729191-99732818 (-)
PWK/PhJ MGP_PWKPhJ_G0021312
 protein coding gene Chr15:96233743-96237371 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021147
 protein coding gene Chr15:99578304-99581937 (-)
WSB/EiJ MGP_WSBEiJ_G0021621
 protein coding gene Chr15:100272905-100276532 (-)



Homology
more
  • Human Ortholog
    RHEBL1, RHEB like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RHEBL1, RHEB like 1
  • Synonyms
    RHEBL1c
  • Links
    NCBI Gene ID: 121268
    neXtProt AC: NX_Q8TAI7
    UniProt: Q8TAI7

  • Chr Location
    12q13.12; chr12:49064676-49070025 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    28 phenotype references
Mice homozygous for a null mutation are viable and fertile with no gross defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    16
  • cDNA Data
    24
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69159 NCBI Gene Model | MGI Sequence Detail 3766 C57BL/6J ±  kb
transcript NM_026967 RefSeq | MGI Sequence Detail 1155 C57BL/6  
polypeptide Q9D8T3 UniProt | EBI | MGI Sequence Detail 184 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 24
    Primer pair 1
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 57
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 5
    Phenotypes 28
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory