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Dtwd1 Gene Detail
Summary
  • Symbol
    Dtwd1
  • Name
    DTW domain containing 1
  • Synonyms
    1810033A06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916435
    NCBI Gene: 69185
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:125994061-126007199 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 61.76 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    441 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916435
protein coding gene Chr2:125993981-126007199 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026438
protein coding gene Chr2:129355924-129368922 (+)
A/J MGP_AJ_G0026401
protein coding gene Chr2:124108241-124121313 (+)
AKR/J MGP_AKRJ_G0026377
protein coding gene Chr2:127652398-127665518 (+)
BALB/cJ MGP_BALBcJ_G0026413
protein coding gene Chr2:124387411-124400834 (+)
C3H/HeJ MGP_C3HHeJ_G0026157
protein coding gene Chr2:128150563-128163927 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026859
protein coding gene Chr2:133484937-133498087 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024236
protein coding gene Chr2:118861814-118875279 (+)
CAST/EiJ MGP_CASTEiJ_G0025618
protein coding gene Chr2:128383697-128402949 (+)
CBA/J MGP_CBAJ_G0026137
protein coding gene Chr2:138354579-138367943 (+)
DBA/2J MGP_DBA2J_G0026271
protein coding gene Chr2:123524005-123537369 (+)
FVB/NJ MGP_FVBNJ_G0026235
protein coding gene Chr2:122190482-122203604 (+)
LP/J MGP_LPJ_G0026376
protein coding gene Chr2:129596148-129617711 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026255
protein coding gene Chr2:142432915-142446864 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026914
protein coding gene Chr2:127690267-127704306 (+)
PWK/PhJ MGP_PWKPhJ_G0025354
protein coding gene Chr2:123072704-123086343 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025156
protein coding gene Chr2:126759311-126772461 (+)
WSB/EiJ MGP_WSBEiJ_G0025692
protein coding gene Chr2:128586044-128599038 (+)



Homology
more
  • Human Ortholog
    DTWD1, DTW domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DTWD1, DTW domain containing 1
  • Synonyms
    MDS009
  • Links
    NCBI Gene ID: 56986
    neXtProt AC: NX_Q8N5C7
    UniProt: Q8N5C7

  • Chr Location
    15q21.2; chr15:49621037-49656232 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023330 Ensembl Gene Model | MGI Sequence Detail 13139 C57BL/6J ±  kb
transcript ENSMUST00000170908 Ensembl | MGI Sequence Detail 1342 Not Applicable  
polypeptide ENSMUSP00000127662 Ensembl | MGI Sequence Detail 304 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory