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Plekha4 Gene Detail
Summary
  • Symbol
    Plekha4
  • Name
    pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
  • Synonyms
    2410005C22Rik, PEPP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916467
    NCBI Gene: 69217
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45175754-45203653 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    877 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916467
 protein coding gene Chr7:45175754-45203653 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032229
 protein coding gene Chr7:45802814-45839967 (+)
A/J MGP_AJ_G0032208
 protein coding gene Chr7:44915096-44945128 (+)
AKR/J MGP_AKRJ_G0032144
 protein coding gene Chr7:46160972-46195651 (+)
BALB/cJ MGP_BALBcJ_G0032220
 protein coding gene Chr7:44905468-44938677 (+)
C3H/HeJ MGP_C3HHeJ_G0031935
 protein coding gene Chr7:46650073-46683521 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032712
 protein coding gene Chr7:48071024-48104167 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029726
 protein coding gene Chr7:47461622-47489006 (+)
CAST/EiJ MGP_CASTEiJ_G0031264
 protein coding gene Chr7:38071317-38103699 (+)
CBA/J MGP_CBAJ_G0031900
 protein coding gene Chr7:49656171-49696186 (+)
DBA/2J MGP_DBA2J_G0032058
 protein coding gene Chr7:44579190-44609304 (+)
FVB/NJ MGP_FVBNJ_G0032009
 protein coding gene Chr7:44371838-44400624 (+)
LP/J MGP_LPJ_G0032136
 protein coding gene Chr7:46501317-46539947 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032046
 protein coding gene Chr7:48357069-48389315 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032728
 protein coding gene Chr7:45374649-45405289 (+)
PWK/PhJ MGP_PWKPhJ_G0030986
 protein coding gene Chr7:37958828-37990024 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030824
 protein coding gene Chr7:33383279-33423720 (+)
WSB/EiJ MGP_WSBEiJ_G0031381
 protein coding gene Chr7:45871380-45906687 (+)



Homology
more
  • Human Ortholog
    PLEKHA4, pleckstrin homology domain containing A4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLEKHA4, pleckstrin homology domain containing A4
  • Synonyms
    PEPP1
  • Links
    NCBI Gene ID: 57664
    neXtProt AC: NX_Q9H4M7
    UniProt: Q9H4M7

  • Chr Location
    19q13.33; chr19:48837092-48868617 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    854
  • Tissues
    20
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69217 NCBI Gene Model | MGI Sequence Detail 27900 C57BL/6J ±  kb
transcript NM_001381849 RefSeq | MGI Sequence Detail 3083 C57BL/6  
polypeptide Q8VC98 UniProt | EBI | MGI Sequence Detail 588 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
less
MGI:2142376
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory