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Qrich1 Gene Detail
Summary
  • Symbol
    Qrich1
  • Name
    glutamine-rich 1
  • Synonyms
    2610028H07Rik, b2b2404Clo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916482
    NCBI Gene: 69232
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108394010-108437366 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    926 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916482
 protein coding gene Chr9:108394005-108437366 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035303
 protein coding gene Chr9:110477818-110527524 (+)
A/J MGP_AJ_G0035282
 protein coding gene Chr9:106429500-106476223 (+)
AKR/J MGP_AKRJ_G0035214
 protein coding gene Chr9:109092976-109143485 (+)
BALB/cJ MGP_BALBcJ_G0035276
 protein coding gene Chr9:106126777-106171850 (+)
C3H/HeJ MGP_C3HHeJ_G0034986
 protein coding gene Chr9:109484071-109535389 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035796
 protein coding gene Chr9:113492289-113537979 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032694
 protein coding gene Chr9:103861058-103904564 (+)
CAST/EiJ MGP_CASTEiJ_G0034297
 protein coding gene Chr9:109454337-109504956 (+)
CBA/J MGP_CBAJ_G0034954
 protein coding gene Chr9:117486610-117539697 (+)
DBA/2J MGP_DBA2J_G0035115
 protein coding gene Chr9:105881781-105932132 (+)
FVB/NJ MGP_FVBNJ_G0035063
 protein coding gene Chr9:104651052-104695020 (+)
LP/J MGP_LPJ_G0035191
 protein coding gene Chr9:110671449-110721614 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035102
 protein coding gene Chr9:119065002-119116449 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035817
 protein coding gene Chr9:109378794-109424305 (+)
PWK/PhJ MGP_PWKPhJ_G0034004
 protein coding gene Chr9:106215727-106260841 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033839
 protein coding gene Chr9:109432701-109487045 (+)
WSB/EiJ MGP_WSBEiJ_G0034418
 protein coding gene Chr9:109262524-109306082 (+)



Homology
more
  • Human Ortholog
    QRICH1, glutamine rich 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    QRICH1, glutamine rich 1
  • Synonyms
    AB-DIP, VERBRAS
  • Links
    NCBI Gene ID: 54870
    neXtProt AC: NX_Q2TAL8
    UniProt: Q2TAL8

  • Chr Location
    3p21.31; chr3:49029707-49094373 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    19 images
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation exhibit cardiovascular defects including overriding aorta, double outlet right ventricle with atrioventricular septal defects and ventricular non-compaction, as well as cleft palate, cystic kidneys, and thymus hypoplasia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    38
  • cDNA Data
    12
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69232 NCBI Gene Model | MGI Sequence Detail 43357 C57BL/6J ±  kb
    transcript NM_001114119 RefSeq | MGI Sequence Detail 3362 C57BL/6  
    polypeptide Q3UA37 UniProt | EBI | MGI Sequence Detail 777 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 13
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:5554538
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 15
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:305998 You K, et al., QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis. Science. 2021 Jan 1;371(6524)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory