Ubl7 MGI Mouse Gene Detail - MGI:1916709 - ubiquitin-like 7 (bone marrow stromal cell-derived)

Symbol

Ubl7
Name

ubiquitin-like 7 (bone marrow stromal cell-derived)
Synonyms

2300004C15Rik

Feature Type

protein coding gene
IDs

MGI:1916709
NCBI Gene: 69459
Alliance

gene page
Transcription Start Sites

12 TSS

Sequence Map

Chr9:57818262-57837251 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 31.63 cM, cytoband C
Mapping Data

3 experiments

SNPs within 2kb

435 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916709	protein coding gene	Chr9:57818262-57837624 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034880	protein coding gene	Chr9:57162332-57181439 (+)
A/J	MGP_AJ_G0034861	protein coding gene	Chr9:55307469-55326605 (+)
AKR/J	MGP_AKRJ_G0034790	protein coding gene	Chr9:56603490-56622560 (+)
BALB/cJ	MGP_BALBcJ_G0034853	protein coding gene	Chr9:55086040-55105074 (+)
C3H/HeJ	MGP_C3HHeJ_G0034563	protein coding gene	Chr9:57065008-57083986 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035372	protein coding gene	Chr9:58748690-58769824 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032283	protein coding gene	Chr9:54605673-54624003 (+)
CAST/EiJ	MGP_CASTEiJ_G0033884	protein coding gene	Chr9:57164651-57183236 (+)
CBA/J	MGP_CBAJ_G0034534	protein coding gene	Chr9:60801268-60820320 (+)
DBA/2J	MGP_DBA2J_G0034693	protein coding gene	Chr9:55171451-55190050 (+)
FVB/NJ	MGP_FVBNJ_G0034635	protein coding gene	Chr9:54412134-54431406 (+)
LP/J	MGP_LPJ_G0034776	protein coding gene	Chr9:57457230-57476505 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034678	protein coding gene	Chr9:62292501-62312415 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035394	protein coding gene	Chr9:56607511-56627146 (+)
PWK/PhJ	MGP_PWKPhJ_G0033589	protein coding gene	Chr9:55212101-55231323 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033423	protein coding gene	Chr9:56883602-56907473 (+)
WSB/EiJ	MGP_WSBEiJ_G0033997	protein coding gene	Chr9:56545138-56564270 (+)

Human Ortholog

UBL7, ubiquitin like 7

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UBL7, ubiquitin like 7
Synonyms

BMSC-UbP, TCBA1
Links

HGNC:28221

NCBI Gene ID: 84993

neXtProt AC: NX_Q96S82

UniProt: Q96S82
Chr Location

15q24.1; chr15:74445977-74461188 (-) GRCh38

MGI Vertebrate Homology

Ubl7 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: UBL7
Gene Tree

Ubl7

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Phenotype Summary

22 phenotypes from 2 alleles in 2 genetic backgrounds
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

14
Endonuclease-mediated

2
Gene trapped

10
Targeted

2
Find Mice (IMSR)

25 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Male mice homozygous for a null mutation show increased susceptibility to Riboviria infection.

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All GO Annotations

8
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

61

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ubl7

ZFIN ubl7a, ubl7b

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All Sequences

109
RefSeq

40
UniProt

8
CCDS

CCDS23234.1

Ensembl

ENSMUSG00000055720 (Evidence)
NCBI Gene

69459

			Length	Strain/Species	Flank
genomic	ENSMUSG00000055720	Ensembl Gene Model \| MGI Sequence Detail	18990	C57BL/6J	± kb
transcript	ENSMUST00000216925	Ensembl \| MGI Sequence Detail	1319	Not Applicable
polypeptide	ENSMUSP00000150925	Ensembl \| MGI Sequence Detail	380	Not Applicable

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UniProt

8 Sequences
Protein Ontology

PR:000017001 ubiquitin-like protein 7

(term hierarchy)
PDB

1X1M
InterPro Domains

IPR009060 UBA-like superfamily

IPR015496 Ubiquilin

IPR015940 Ubiquitin-associated domain

IPR000626 Ubiquitin-like domain

IPR029071 Ubiquitin-like domain superfamily

IPR047878 Ubiquitin-like protein 7, UBA domain

IPR047877 Ubiquitin-like protein 7, ubiquitin-like domain

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All nucleic 61

cDNA 61

Microarray probesets 3

Summaries

All 33

Gene Ontology 4

Phenotypes 9
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ubl7:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr85332	Chr9:57817756-57817773 (+)	-497 bp
Tssr85333	Chr9:57817789-57817813 (+)	-461 bp
Tssr85334	Chr9:57817825-57817835 (+)	-432 bp
Tssr85335	Chr9:57818257-57818306 (+)	20 bp
Tssr85336	Chr9:57818308-57818319 (+)	52 bp
Tssr85337	Chr9:57818322-57818333 (+)	66 bp
Tssr85338	Chr9:57818377-57818378 (+)	116 bp
Tssr85339	Chr9:57818385-57818398 (+)	130 bp
Tssr85340	Chr9:57818422-57818433 (+)	166 bp
Tssr85341	Chr9:57829753-57829785 (+)	11,507 bp
Tssr85342	Chr9:57829803-57829821 (+)	11,550 bp
Tssr85343	Chr9:57829850-57829864 (+)	11,595 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24