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Ten1 Gene Detail
Summary
  • Symbol
    Ten1
  • Name
    TEN1 telomerase capping complex subunit
  • Synonyms
    2310004N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916785
    NCBI Gene: 69535
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116089681-116106144 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 81.00 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    553 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916785
protein coding gene Chr11:116089681-116106144 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019419
protein coding gene Chr11:120293265-120313242 (+)
A/J MGP_AJ_G0019388
protein coding gene Chr11:115037951-115054819 (+)
AKR/J MGP_AKRJ_G0019358
protein coding gene Chr11:118461487-118484083 (+)
BALB/cJ MGP_BALBcJ_G0019362
protein coding gene Chr11:115449672-115466377 (+)
C3H/HeJ MGP_C3HHeJ_G0019168
protein coding gene Chr11:118816914-118835638 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019812
protein coding gene Chr11:123985264-124001699 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017435
protein coding gene Chr11:112050011-112066277 (+)
CAST/EiJ MGP_CASTEiJ_G0018723
protein coding gene Chr11:120177745-120195652 (+)
CBA/J MGP_CBAJ_G0019140
protein coding gene Chr11:128872843-128889319 (+)
DBA/2J MGP_DBA2J_G0019251
protein coding gene Chr11:114452902-114471710 (+)
FVB/NJ MGP_FVBNJ_G0019243
protein coding gene Chr11:113968730-113985596 (+)
LP/J MGP_LPJ_G0019321
protein coding gene Chr11:120672473-120692419 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019276
protein coding gene Chr11:127953472-127973440 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019850
protein coding gene Chr11:119123370-119140440 (+)
PWK/PhJ MGP_PWKPhJ_G0018487
protein coding gene Chr11:115788619-115805094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018280
protein coding gene Chr11:118879891-118895863 (+)
WSB/EiJ MGP_WSBEiJ_G0018775
protein coding gene Chr11:119094536-119111859 (+)



Homology
more
  • Human Ortholog
    TEN1, TEN1 subunit of CST complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEN1, TEN1 subunit of CST complex
  • Synonyms
    C17orf106
  • Links
    NCBI Gene ID: 100134934
    neXtProt AC: NX_Q86WV5
    UniProt: Q86WV5

  • Chr Location
    chr17:75979240-76000586 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69535 NCBI Gene Model | MGI Sequence Detail 16464 C57BL/6J ±  kb
transcript NM_027107 RefSeq | MGI Sequence Detail 919 C57BL/6  
polypeptide Q9D7K2 UniProt | EBI | MGI Sequence Detail 161 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory