About   Help   FAQ
Capns2 Gene Detail
Summary
  • Symbol
    Capns2
  • Name
    calpain, small subunit 2
  • Synonyms
    2310005G05Rik, 30K-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916793
    NCBI Gene: 69543
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:93628035-93629039 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 44.99 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916793
 protein coding gene Chr8:93628023-93629039 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033938
 protein coding gene Chr8:94220358-94221358 (+)
A/J MGP_AJ_G0033921
 protein coding gene Chr8:90504479-90505479 (+)
AKR/J MGP_AKRJ_G0033847
 protein coding gene Chr8:93051191-93052191 (+)
BALB/cJ MGP_BALBcJ_G0033913
 protein coding gene Chr8:90661365-90662365 (+)
C3H/HeJ MGP_C3HHeJ_G0033623
 protein coding gene Chr8:93763034-93764034 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034434
 protein coding gene Chr8:97688392-97689392 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031375
 protein coding gene Chr8:84432908-84433908 (+)
CAST/EiJ MGP_CASTEiJ_G0032955
 protein coding gene Chr8:93325455-93326455 (+)
CBA/J MGP_CBAJ_G0033599
 protein coding gene Chr8:100937130-100938130 (+)
DBA/2J MGP_DBA2J_G0033753
 protein coding gene Chr8:90048578-90049578 (+)
FVB/NJ MGP_FVBNJ_G0033700
 protein coding gene Chr8:88988011-88989011 (+)
LP/J MGP_LPJ_G0033845
 protein coding gene Chr8:94343608-94344608 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033742
 protein coding gene Chr8:103289009-103290009 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034452
 protein coding gene Chr8:93165186-93166186 (+)
PWK/PhJ MGP_PWKPhJ_G0032657
 protein coding gene Chr8:89400226-89401226 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032494
 protein coding gene Chr8:92016837-92017842 (+)
WSB/EiJ MGP_WSBEiJ_G0033067
 protein coding gene Chr8:93626999-93627999 (+)



Homology
more
  • Human Ortholog
    CAPNS2, calpain small subunit 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAPNS2, calpain small subunit 2
  • Synonyms
    CSS2
  • Links
    NCBI Gene ID: 84290
    neXtProt AC: NX_Q96L46
    UniProt: Q96L46

  • Chr Location
    16q12.2; chr16:55566684-55567687 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078144 Ensembl Gene Model | MGI Sequence Detail 1005 C57BL/6J ±  kb
transcript ENSMUST00000104947 Ensembl | MGI Sequence Detail 1005 Not Applicable  
polypeptide ENSMUSP00000100553 Ensembl | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Gene Ontology 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:125385 Hata S, et al., Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains. J Biol Chem. 2007 Sep 21;282(38):27847-56
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory