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Wdr5b Gene Detail
Summary
  • Symbol
    Wdr5b
  • Name
    WD repeat domain 5B
  • Synonyms
    2310009C03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916794
    NCBI Gene: 69544
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:35861560-35863344 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916794
 protein coding gene Chr16:35861560-35864298 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022776
 protein coding gene Chr16:34408789-34410572 (+)
A/J MGP_AJ_G0022741
 protein coding gene Chr16:32734009-32735792 (+)
AKR/J MGP_AKRJ_G0022714
 protein coding gene Chr16:33885040-33886823 (+)
BALB/cJ MGP_BALBcJ_G0022743
 protein coding gene Chr16:32854675-32856458 (+)
C3H/HeJ MGP_C3HHeJ_G0022508
 protein coding gene Chr16:34008854-34010640 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023192
 protein coding gene Chr16:35146669-35148452 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020710
 protein coding gene Chr16:33091047-33092824 (+)
CAST/EiJ MGP_CASTEiJ_G0022036
 protein coding gene Chr16:34238166-34239952 (+)
CBA/J MGP_CBAJ_G0022478
 protein coding gene Chr16:36571343-36573129 (+)
DBA/2J MGP_DBA2J_G0022611
 protein coding gene Chr16:32556984-32558770 (+)
FVB/NJ MGP_FVBNJ_G0022586
 protein coding gene Chr16:32551215-32552998 (+)
LP/J MGP_LPJ_G0022678
 protein coding gene Chr16:34135084-34136867 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022605
 protein coding gene Chr16:35836726-35838509 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023204
 protein coding gene Chr16:33944429-33946212 (+)
PWK/PhJ MGP_PWKPhJ_G0021777
 protein coding gene Chr16:32976027-32977810 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021608
 protein coding gene Chr16:33745413-33747202 (+)
WSB/EiJ MGP_WSBEiJ_G0022080
 protein coding gene Chr16:33869254-33871040 (+)



Homology
more
  • Human Ortholog
    WDR5B, WD repeat domain 5B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR5B, WD repeat domain 5B
  • Links
    NCBI Gene ID: 54554
    neXtProt AC: NX_Q86VZ2
    UniProt: Q86VZ2

  • Chr Location
    3q21.1; chr3:122411846-122416062 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69544 NCBI Gene Model | MGI Sequence Detail 1785 C57BL/6J ±  kb
transcript NM_027113 RefSeq | MGI Sequence Detail 1806 C57BL/6  
polypeptide Q9D7H2 UniProt | EBI | MGI Sequence Detail 328 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146465
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory