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Clybl Gene Detail
Summary
  • Symbol
    Clybl
  • Name
    citrate lyase beta like
  • Synonyms
    0610033J05Rik, 2310014M14Rik, Clb
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916884
    NCBI Gene: 69634
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:122419116-122639646 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 65.86 cM, cytoband E5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4729 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916884
 protein coding gene Chr14:122408289-122639646 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021669
 protein coding gene Chr14:120074542-120312492 (+)
A/J MGP_AJ_G0021629
 protein coding gene Chr14:115413283-115639156 (+)
AKR/J MGP_AKRJ_G0021605
 protein coding gene Chr14:119151492-119380699 (+)
BALB/cJ MGP_BALBcJ_G0021635
 protein coding gene Chr14:115958715-116189226 (+)
C3H/HeJ MGP_C3HHeJ_G0021413
 protein coding gene Chr14:119035523-119275555 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022075
 protein coding gene Chr14:124678506-124930190 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019613
 protein coding gene Chr14:111279154-111500835 (+)
CAST/EiJ MGP_CASTEiJ_G0020928
 protein coding gene Chr14:116955415-117189586 (+)
CBA/J MGP_CBAJ_G0021381
 protein coding gene Chr14:129426190-129676683 (+)
DBA/2J MGP_DBA2J_G0021504
 protein coding gene Chr14:115273434-115498329 (+)
FVB/NJ MGP_FVBNJ_G0021482
 protein coding gene Chr14:113626969-113850932 (+)
LP/J MGP_LPJ_G0021572
 protein coding gene Chr14:120986482-121220849 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021509
 protein coding gene Chr14:134413372-134661762 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022098
 protein coding gene Chr14:118746555-118978025 (+)
PWK/PhJ MGP_PWKPhJ_G0020672
 protein coding gene Chr14:112330964-112559021 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020510
 protein coding gene Chr14:114923266-115146600 (+)
WSB/EiJ MGP_WSBEiJ_G0020984
 protein coding gene Chr14:119411074-119643423 (+)



Homology
more
  • Human Ortholog
    CLYBL, citramalyl-CoA lyase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLYBL, citramalyl-CoA lyase
  • Synonyms
    CLB
  • Links
    NCBI Gene ID: 171425
    neXtProt AC: NX_Q8N0X4
    UniProt: Q8N0X4

  • Chr Location
    13q32.3; chr13:99606669-99909459 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    865
  • Tissues
    112
  • cDNA Data
    40
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025545 Ensembl Gene Model | MGI Sequence Detail 220531 C57BL/6J ±  kb
transcript ENSMUST00000026625 Ensembl | MGI Sequence Detail 1231 Not Applicable  
polypeptide ENSMUSP00000026625 Ensembl | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 41
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923514, MGI:2145609
References
more
  • Summaries
    All 45
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:350916 Yu Z, et al., Itaconate alleviates diet-induced obesity via activation of brown adipocyte thermogenesis. Cell Rep. 2024 May 28;43(5):114142
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory