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Psmg4 Gene Detail
Summary
  • Symbol
    Psmg4
  • Name
    proteasome (prosome, macropain) assembly chaperone 4
  • Synonyms
    2310047M15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916916
    NCBI Gene: 69666
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34346947-34362155 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 14.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916916
protein coding gene Chr13:34346947-34362156 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020449
protein coding gene Chr13:32272859-32284236 (+)
A/J MGP_AJ_G0020403
protein coding gene Chr13:31330123-31338104 (+)
AKR/J MGP_AKRJ_G0020381
protein coding gene Chr13:32067925-32077667 (+)
BALB/cJ MGP_BALBcJ_G0020399
protein coding gene Chr13:31397255-31405385 (+)
C3H/HeJ MGP_C3HHeJ_G0020198
protein coding gene Chr13:32012439-32021827 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020832
protein coding gene Chr13:33351606-33360110 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018419
protein coding gene Chr13:29637016-29644853 (+)
CAST/EiJ MGP_CASTEiJ_G0019713
protein coding gene Chr13:31657991-31665904 (+)
CBA/J MGP_CBAJ_G0020159
protein coding gene Chr13:34798106-34806094 (+)
DBA/2J MGP_DBA2J_G0020281
protein coding gene Chr13:30859553-30867534 (+)
FVB/NJ MGP_FVBNJ_G0020260
protein coding gene Chr13:30430856-30439810 (+)
LP/J MGP_LPJ_G0020356
protein coding gene Chr13:32512606-32520603 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020290
protein coding gene Chr13:35012033-35024434 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020875
protein coding gene Chr13:31732112-31740093 (+)
PWK/PhJ MGP_PWKPhJ_G0019468
protein coding gene Chr13:30972632-30980867 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019295
protein coding gene Chr13:30376233-30383995 (+)
WSB/EiJ MGP_WSBEiJ_G0019775
protein coding gene Chr13:32084084-32092064 (+)



Homology
more
  • Human Ortholog
    PSMG4, proteasome assembly chaperone 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMG4, proteasome assembly chaperone 4
  • Synonyms
    bA506K6.2, C6orf86, PAC4, Pba4
  • Links
    NCBI Gene ID: 389362
    neXtProt AC: NX_Q5JS54
    UniProt: Q5JS54

  • Chr Location
    6p25.2; chr6:3231403-3303373 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    47
  • Chemically induced (other)
    1
  • Gene trapped
    45
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Psmg4
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69666 NCBI Gene Model | MGI Sequence Detail 15209 C57BL/6J ±  kb
transcript NM_001101430 RefSeq | MGI Sequence Detail 577 C57BL/6  
polypeptide P0C7N9 UniProt | EBI | MGI Sequence Detail 123 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory