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Tm2d2 Gene Detail
Summary
  • Symbol
    Tm2d2
  • Name
    TM2 domain containing 2
  • Synonyms
    2410018G23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916992
    NCBI Gene: 69742
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:25507227-25513276 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 13.70 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916992
 protein coding gene Chr8:25507227-25513276 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033477
 protein coding gene Chr8:23015605-23021014 (+)
A/J MGP_AJ_G0033457
 protein coding gene Chr8:22209593-22215002 (+)
AKR/J MGP_AKRJ_G0033382
 protein coding gene Chr8:22925961-22931370 (+)
BALB/cJ MGP_BALBcJ_G0033453
 protein coding gene Chr8:22354065-22359474 (+)
C3H/HeJ MGP_C3HHeJ_G0033167
 protein coding gene Chr8:23143178-23148587 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033969
 protein coding gene Chr8:23958611-23966386 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030919
 protein coding gene Chr8:19492708-19498484 (+)
CAST/EiJ MGP_CASTEiJ_G0032493
 protein coding gene Chr8:22568929-22574351 (+)
CBA/J MGP_CBAJ_G0033142
 protein coding gene Chr8:24878267-24883676 (+)
DBA/2J MGP_DBA2J_G0033297
 protein coding gene Chr8:22179909-22185318 (+)
FVB/NJ MGP_FVBNJ_G0033241
 protein coding gene Chr8:21980154-21985563 (+)
LP/J MGP_LPJ_G0033386
 protein coding gene Chr8:23006538-23011947 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033284
 protein coding gene Chr8:24396950-24402359 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033988
 protein coding gene Chr8:22878368-22883777 (+)
PWK/PhJ MGP_PWKPhJ_G0032204
 protein coding gene Chr8:21783935-21789507 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032038
 protein coding gene Chr8:22214929-22220346 (+)
WSB/EiJ MGP_WSBEiJ_G0032609
 protein coding gene Chr8:23078304-23083709 (+)



Homology
more
  • Human Ortholog
    TM2D2, TM2 domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM2D2, TM2 domain containing 2
  • Synonyms
    BLP1
  • Links
    NCBI Gene ID: 83877
    neXtProt AC: NX_Q9BX73
    UniProt: Q9BX73

  • Chr Location
    8p11.22; chr8:38988808-38996990 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    111
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69742 NCBI Gene Model | MGI Sequence Detail 6050 C57BL/6J ±  kb
    transcript NM_027194 RefSeq | MGI Sequence Detail 1298 C57BL/6  
    polypeptide Q8R0I4 UniProt | EBI | MGI Sequence Detail 213 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 111
      cDNA 111

      Microarray probesets 9
    References
    more
    • Summaries
      All 30
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory