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Tlcd2 Gene Detail
Summary
  • Symbol
    Tlcd2
  • Name
    TLC domain containing 2
  • Synonyms
    2010305C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917141
    NCBI Gene: 380712
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:75358771-75361725 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 45.91 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917141
 protein coding gene Chr11:75352541-75361725 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018713
 protein coding gene Chr11:76208791-76217878 (+)
A/J MGP_AJ_G0018679
 protein coding gene Chr11:73377170-73386144 (+)
AKR/J MGP_AKRJ_G0018649
 protein coding gene Chr11:75596980-75608887 (+)
BALB/cJ MGP_BALBcJ_G0018653
 protein coding gene Chr11:73748370-73757955 (+)
C3H/HeJ MGP_C3HHeJ_G0018466
 protein coding gene Chr11:75613842-75624743 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019104
 protein coding gene Chr11:78594317-78603169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016739
 protein coding gene Chr11:70387104-70398379 (+)
CAST/EiJ MGP_CASTEiJ_G0018020
 protein coding gene Chr11:76006781-76016603 (+)
CBA/J MGP_CBAJ_G0018436
 protein coding gene Chr11:82046619-82060432 (+)
DBA/2J MGP_DBA2J_G0018545
 protein coding gene Chr11:72981951-72991039 (+)
FVB/NJ MGP_FVBNJ_G0018535
 protein coding gene Chr11:72541698-72551408 (+)
LP/J MGP_LPJ_G0018616
 protein coding gene Chr11:76798358-76807232 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018561
 protein coding gene Chr11:82612442-82621297 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019144
 protein coding gene Chr11:75806173-75818458 (+)
PWK/PhJ MGP_PWKPhJ_G0017791
 protein coding gene Chr11:73677642-73686532 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017582
 protein coding gene Chr11:75359222-75368019 (+)
WSB/EiJ MGP_WSBEiJ_G0018073
 protein coding gene Chr11:75613403-75624115 (+)



Homology
more
  • Human Ortholog
    TLCD2, TLC domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TLCD2, TLC domain containing 2
  • Links
    NCBI Gene ID: 727910
    neXtProt AC: NX_A6NGC4
    UniProt: A6NGC4

  • Chr Location
    17p13.3; chr17:1702816-1710377 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    8
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380712 NCBI Gene Model | MGI Sequence Detail 2955 C57BL/6J ±  kb
transcript NM_027249 RefSeq | MGI Sequence Detail 1424 C57BL/6  
polypeptide Q8VC26 UniProt | EBI | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 1
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory