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Polr2i Gene Detail
Summary
  • Symbol
    Polr2i
  • Name
    polymerase (RNA) II (DNA directed) polypeptide I
  • Synonyms
    2810002B19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917170
    NCBI Gene: 69920
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:29931499-29932812 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 17.34 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917170
 protein coding gene Chr7:29931373-29932815 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032007
 protein coding gene Chr7:29213237-29214315 (+)
A/J MGP_AJ_G0031984
 protein coding gene Chr7:28443698-28444759 (+)
AKR/J MGP_AKRJ_G0031917
 protein coding gene Chr7:29171365-29172443 (+)
BALB/cJ MGP_BALBcJ_G0031991
 protein coding gene Chr7:28619049-28620126 (+)
C3H/HeJ MGP_C3HHeJ_G0031710
 protein coding gene Chr7:29612683-29613746 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032456
 protein coding gene Chr7:30159618-30160681 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029507
 protein coding gene Chr7:29479536-29480623 (+)
CAST/EiJ MGP_CASTEiJ_G0031044
 protein coding gene Chr7:22866084-22867160 (+)
CBA/J MGP_CBAJ_G0031676
 protein coding gene Chr7:31609845-31613841 (+)
DBA/2J MGP_DBA2J_G0031828
 protein coding gene Chr7:28172418-28173495 (+)
FVB/NJ MGP_FVBNJ_G0031785
 protein coding gene Chr7:28285561-28286640 (+)
LP/J MGP_LPJ_G0031909
 protein coding gene Chr7:29537088-29538163 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031821
 protein coding gene Chr7:30871843-30872916 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032485
 protein coding gene Chr7:28668891-28669959 (+)
PWK/PhJ MGP_PWKPhJ_G0030770
 protein coding gene Chr7:23204461-23205540 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030603
 protein coding gene Chr7:19668644-19669711 (+)
WSB/EiJ MGP_WSBEiJ_G0031154
 protein coding gene Chr7:29048824-29049898 (+)



Homology
more
  • Human Ortholog
    POLR2I, RNA polymerase II subunit I
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR2I, RNA polymerase II subunit I
  • Synonyms
    hRPB14.5, RPB9
  • Links
    NCBI Gene ID: 5438
    neXtProt AC: NX_P36954
    UniProt: P36954

  • Chr Location
    19q13.12; chr19:36113709-36115213 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    817
  • Tissues
    111
  • cDNA Data
    72
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69920 NCBI Gene Model | MGI Sequence Detail 1314 C57BL/6J ±  kb
transcript NM_027259 RefSeq | MGI Sequence Detail 707 Not Specified  
polypeptide P60898 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000012995 DNA-directed RNA polymerase II subunit RPB9
    (term hierarchy)
  • InterPro Domains
    IPR001529 DNA-directed RNA polymerase, M/15kDa subunit
    IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site
    IPR012164 DNA-directed RNA polymerase subunit/transcription factor S
    IPR034012 Pol II subunit B9, C-terminal zinc ribbon
    IPR001222 Zinc finger, TFIIS-type
Molecular
Reagents
less
  • All nucleic 73
    cDNA 72
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:357241 Iyyappan R, et al., The translational oscillation in oocyte and early embryo development. Nucleic Acids Res. 2023 Dec 11;51(22):12076-12091
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory