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Dancr Gene Detail
Summary
  • Symbol
    Dancr
  • Name
    differentiation antagonizing non-protein coding RNA
  • Synonyms
    2700023E23Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1917286
    NCBI Gene: 70036
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:74253780-74254998 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 39.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917286
 lncRNA gene Chr5:74253695-74256067 (+)
129S1/SvImJ MGP_129S1SvImJ_G0006667
 lincRNA gene Chr5:74154572-74156925 (+)
A/J MGP_AJ_G0006661
 lincRNA gene Chr5:71349402-71351747 (+)
AKR/J MGP_AKRJ_G0006631
 lincRNA gene Chr5:73675341-73677685 (+)
BALB/cJ MGP_BALBcJ_G0006636
 lincRNA gene Chr5:72058029-72060373 (+)
C3H/HeJ MGP_C3HHeJ_G0006582
 lincRNA gene Chr5:74058236-74060591 (+)
C57BL/6NJ MGP_C57BL6NJ_G0006801
 lincRNA gene Chr5:77186857-77194417 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006060
 lincRNA gene Chr5:67015891-67018221 (+)
CAST/EiJ MGP_CASTEiJ_G0006505
 lincRNA gene Chr5:73141664-73144025 (+)
CBA/J MGP_CBAJ_G0006563
 lincRNA gene Chr5:79707314-79709669 (+)
DBA/2J MGP_DBA2J_G0006583
 lincRNA gene Chr5:71419202-71421557 (+)
FVB/NJ MGP_FVBNJ_G0006608
 lincRNA gene Chr5:70573324-70576000 (+)
LP/J MGP_LPJ_G0006668
 lincRNA gene Chr5:74585094-74587425 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0006592
 lincRNA gene Chr5:82978419-82980770 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0006803
 lincRNA gene Chr5:73209468-73211817 (+)
PWK/PhJ MGP_PWKPhJ_G0006444
 lincRNA gene Chr5:70395102-70397556 (+)
SPRET/EiJ MGP_SPRETEiJ_G0006351
 lincRNA gene Chr5:72566898-72569239 (+)
WSB/EiJ MGP_WSBEiJ_G0006556
 lincRNA gene Chr5:73503448-73507037 (+)



Homology
more
  • Human Ortholog
    DANCR, differentiation antagonizing non-protein coding RNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DANCR, differentiation antagonizing non-protein coding RNA
  • Synonyms
    AGU2, ANCR, KIAA0114, lncRNA-ANCR, SNHG13
  • Links
    NCBI Gene ID: 57291

  • Chr Location
    4q12; chr4:52712325-52723623 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    363 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice for a null allele exhibit reduced hepatocellular carcinoma development and hepatic fibrosis in a DEN-CCl4-induced carcinogenesis model.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    17
  • cDNA Data
    7
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      35
    • RefSeq
      3
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70036 NCBI Gene Model | MGI Sequence Detail 1219 C57BL/6J ±  kb
    transcript NR_145133 RefSeq | MGI Sequence Detail 1219 C57BL/6  
    polypeptide Q3T987 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 381
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 1
      Phenotypes 363
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:353367 Taketomi Y, et al., Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity. 2024 Aug 13;57(8):1828-1847.e11
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory