Ccdc89 Gene Detail

Summary

• Symbol
  Ccdc89
• Name
  coiled-coil domain containing 89
• Synonyms
  1700019B01Rik, BOIP

• Feature Type
  protein coding gene
• IDs
  MGI:1917304
  NCBI Gene: 70054
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr7:90075785-90077877 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 50.58 cM, cytoband E1
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  170 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917304	protein coding gene	Chr7:90075520-90077877 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0032506	protein coding gene	Chr7:92850578-92852926 (+)
A/J	MGP_AJ_G0032480	protein coding gene	Chr7:90612076-90614424 (+)
AKR/J	MGP_AKRJ_G0032416	protein coding gene	Chr7:92729504-92731852 (+)
BALB/cJ	MGP_BALBcJ_G0032491	protein coding gene	Chr7:90256913-90259261 (+)
C3H/HeJ	MGP_C3HHeJ_G0032206	protein coding gene	Chr7:93118354-93120702 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032989	protein coding gene	Chr7:96475622-96477970 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029984	protein coding gene	Chr7:93495813-93498155 (+)
CAST/EiJ	MGP_CASTEiJ_G0031533	protein coding gene	Chr7:84557990-84560335 (+)
CBA/J	MGP_CBAJ_G0032173	protein coding gene	Chr7:99685830-99688178 (+)
DBA/2J	MGP_DBA2J_G0032325	protein coding gene	Chr7:89046887-89049235 (+)
FVB/NJ	MGP_FVBNJ_G0032281	protein coding gene	Chr7:88913906-88916254 (+)
LP/J	MGP_LPJ_G0032414	protein coding gene	Chr7:94123910-94126258 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032315	protein coding gene	Chr7:100694441-100696789 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033011	protein coding gene	Chr7:92013641-92015989 (+)
PWK/PhJ	MGP_PWKPhJ_G0031251	protein coding gene	Chr7:82087093-82089434 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031094	protein coding gene	Chr7:79335175-79337522 (+)
WSB/EiJ	MGP_WSBEiJ_G0031650	protein coding gene	Chr7:92686997-92689345 (+)

Homology

• Human Ortholog
  CCDC89, coiled-coil domain containing 89

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CCDC89, coiled-coil domain containing 89
  
• Links
  HGNC:26762

  NCBI Gene ID: 220388

  neXtProt AC: NX_Q8N998

  UniProt: Q8N998

  
  
• Chr Location
  11q14.1; chr11:85683848-85686195 (-)  GRCh38

---

• MGI Vertebrate Homology
  Ccdc89 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CCDC89
• Gene Tree
  Ccdc89
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  29 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (other)
  1
• Endonuclease-mediated
  3
• Gene trapped
  1
• Radiation induced
  3
• Genomic Mutations
  4 involving Ccdc89
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  5
• GO References
  2

Expression

• Assay Results
  721
• Tissues
  14
• cDNA Data
  11
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA CCDC89
  Xenbase ccdc89

Sequences &
Gene Models

• All Sequences
  32
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS52308.1

• Ensembl
  ENSMUSG00000044362 (Evidence)
• NCBI Gene
  70054

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000044362	Ensembl Gene Model | MGI Sequence Detail	2093	C57BL/6J
transcript	ENSMUST00000061391	Ensembl | MGI Sequence Detail	2093	Not Applicable
polypeptide	ENSMUSP00000060309	Ensembl | MGI Sequence Detail	370	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000032630 coiled-coil domain-containing protein 89
  (term hierarchy)
• InterPro Domains
  IPR043450 Coiled-coil domain-containing protein 89-like

Molecular
Reagents

• All nucleic 13

  cDNA 11

  Other 2

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2142140

References

• Summaries
  All 53

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 29
• Earliest
  J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Ccdc89:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr67759	Chr7:90075702-90075710 (+)	-79 bp
Tssr67760	Chr7:90075716-90075752 (+)	-51 bp
Tssr67761	Chr7:90075763-90075785 (+)	-11 bp