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Prrg1 Gene Detail
Summary
  • Symbol
    Prrg1
  • Name
    proline rich Gla (G-carboxyglutamic acid) 1
  • Synonyms
    2010007L08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917364
    NCBI Gene: 546336
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:77493219-77627502 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.34 cM, cytoband A7.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2551 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917364
 protein coding gene ChrX:77493216-77627539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035879
 protein coding gene ChrX:74320636-74461415 (-)
A/J MGP_AJ_G0035865
 protein coding gene ChrX:74589245-74718133 (-)
AKR/J MGP_AKRJ_G0035783
 protein coding gene ChrX:76537206-76672900 (-)
BALB/cJ MGP_BALBcJ_G0035845
 protein coding gene ChrX:73511574-73645626 (-)
C3H/HeJ MGP_C3HHeJ_G0035556
 protein coding gene ChrX:74750767-74899965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036377
 protein coding gene ChrX:76625657-76763767 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033207
 protein coding gene ChrX:73972072-74100572 (-)
CAST/EiJ MGP_CASTEiJ_G0034844
 protein coding gene ChrX:60002947-60143305 (-)
CBA/J MGP_CBAJ_G0035530
 protein coding gene ChrX:78674234-78844644 (-)
DBA/2J MGP_DBA2J_G0035686
 protein coding gene ChrX:74010133-74152264 (-)
FVB/NJ MGP_FVBNJ_G0035625
 protein coding gene ChrX:73248006-73378919 (-)
LP/J MGP_LPJ_G0035774
 protein coding gene ChrX:75167957-75306547 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035662
 protein coding gene ChrX:81493624-81630374 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036403
 protein coding gene ChrX:74130931-74263730 (-)
PWK/PhJ MGP_PWKPhJ_G0034542
 protein coding gene ChrX:58065444-58208056 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034373
 protein coding gene ChrX:60899629-61044182 (-)
WSB/EiJ MGP_WSBEiJ_G0034983
 protein coding gene ChrX:73315526-73451124 (-)



Homology
more
  • Human Ortholog
    PRRG1, proline rich and Gla domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRRG1, proline rich and Gla domain 1
  • Synonyms
    PRGP1
  • Links
    NCBI Gene ID: 5638
    neXtProt AC: NX_O14668
    UniProt: O14668

  • Chr Location
    Xp21.1; chrX:37349309-37492702 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047996 Ensembl Gene Model | MGI Sequence Detail 134284 C57BL/6J ±  kb
transcript ENSMUST00000114025 Ensembl | MGI Sequence Detail 3964 Not Applicable  
polypeptide ENSMUSP00000109659 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR017857 Coagulation factor-like, Gla domain superfamily
    IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
    IPR035972 Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
    IPR050442 Peptidase S1 family, coagulation factors
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 4
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory