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Dpf3 Gene Detail
Summary
  • Symbol
    Dpf3
  • Name
    double PHD fingers 3
  • Synonyms
    2810403B03Rik, cer-d4, CERD4, Gm18872
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917377
    NCBI Gene: 70127
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:83260519-83534490 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 38.64 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917377
protein coding gene Chr12:83260519-83534510 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019912
protein coding gene Chr12:83817653-84118668 (-)
A/J MGP_AJ_G0019869
protein coding gene Chr12:80654202-80936567 (-)
AKR/J MGP_AKRJ_G0019845
protein coding gene Chr12:82831431-83123374 (-)
BALB/cJ MGP_BALBcJ_G0019849
protein coding gene Chr12:81002209-81281879 (-)
C3H/HeJ MGP_C3HHeJ_G0019655
protein coding gene Chr12:83296636-83591683 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020301
protein coding gene Chr12:86218492-86523517 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017918
protein coding gene Chr12:77594572-77868213 (-)
CAST/EiJ MGP_CASTEiJ_G0019204
protein coding gene Chr12:78244496-78532346 (-)
CBA/J MGP_CBAJ_G0019626
protein coding gene Chr12:89530822-89855780 (-)
DBA/2J MGP_DBA2J_G0019741
protein coding gene Chr12:80215529-80490641 (-)
FVB/NJ MGP_FVBNJ_G0019727
protein coding gene Chr12:79148158-79430786 (-)
LP/J MGP_LPJ_G0019813
protein coding gene Chr12:83689218-83990800 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019766
protein coding gene Chr12:92535068-92832372 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020335
protein coding gene Chr12:82437812-82724361 (-)
PWK/PhJ MGP_PWKPhJ_G0018968
protein coding gene Chr12:74675194-74960008 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018763
protein coding gene Chr12:76891424-77173975 (-)
WSB/EiJ MGP_WSBEiJ_G0019256
protein coding gene Chr12:83082063-83383694 (-)



Homology
more
  • Human Ortholog
    DPF3, double PHD fingers 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DPF3, double PHD fingers 3
  • Synonyms
    BAF45C, CERD4, SMARCG3
  • Links
    NCBI Gene ID: 8110
    neXtProt AC: NX_Q92784
    UniProt: Q92784

  • Chr Location
    14q24.2; chr14:72609034-72894101 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display no detectable phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021221 Ensembl Gene Model | MGI Sequence Detail 273972 C57BL/6J ±  kb
    transcript ENSMUST00000178756 Ensembl | MGI Sequence Detail 3135 Not Applicable  
    polypeptide ENSMUSP00000136280 Ensembl | MGI Sequence Detail 378 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      Genomic 1
      cDNA 15
      Primer pair 4
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2145092, MGI:5011057
    References
    more
    • Summaries
      All 71
      Developmental Gene Expression 16
      Gene Ontology 17
      Phenotypes 13
    • Earliest
      J:35263 Wang W, et al., Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 1996 Sep 1;10(17):2117-30
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory