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Lrch3 Gene Detail
Summary
  • Symbol
    Lrch3
  • Name
    leucine-rich repeats and calponin homology (CH) domain containing 3
  • Synonyms
    2210409B11Rik, LOC385628
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917394
    NCBI Gene: 70144
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:32734470-32836017 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 23.46 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2396 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917394
 protein coding gene Chr16:32734452-32836399 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022749
 protein coding gene Chr16:31041555-31152673 (+)
A/J MGP_AJ_G0022714
 protein coding gene Chr16:29555840-29680448 (+)
AKR/J MGP_AKRJ_G0022687
 protein coding gene Chr16:30617579-30725369 (+)
BALB/cJ MGP_BALBcJ_G0022716
 protein coding gene Chr16:29696748-29799055 (+)
C3H/HeJ MGP_C3HHeJ_G0022481
 protein coding gene Chr16:30741839-30851463 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023165
 protein coding gene Chr16:31706935-31827426 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020683
 protein coding gene Chr16:29922746-30034657 (+)
CAST/EiJ MGP_CASTEiJ_G0022009
 protein coding gene Chr16:30893640-30999391 (+)
CBA/J MGP_CBAJ_G0022451
 protein coding gene Chr16:32978638-33103833 (+)
DBA/2J MGP_DBA2J_G0022584
 protein coding gene Chr16:29403366-29504859 (+)
FVB/NJ MGP_FVBNJ_G0022559
 protein coding gene Chr16:29388675-29495648 (+)
LP/J MGP_LPJ_G0022651
 protein coding gene Chr16:30805484-30918645 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022578
 protein coding gene Chr16:32391265-32509240 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023177
 protein coding gene Chr16:30606884-30731529 (+)
PWK/PhJ MGP_PWKPhJ_G0021748
 protein coding gene Chr16:29739839-29845377 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021579
 protein coding gene Chr16:30405511-30527849 (+)
WSB/EiJ MGP_WSBEiJ_G0022053
 protein coding gene Chr16:30573956-30699432 (+)



Homology
more
  • Human Ortholog
    LRCH3, leucine rich repeats and calponin homology domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRCH3, leucine rich repeats and calponin homology domain containing 3
  • Links
    NCBI Gene ID: 84859
    neXtProt AC: NX_Q96II8
    UniProt: Q96II8

  • Chr Location
    3q29; chr3:197791226-197888436 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022801 Ensembl Gene Model | MGI Sequence Detail 101548 C57BL/6J ±  kb
transcript ENSMUST00000135193 Ensembl | MGI Sequence Detail 2794 Not Applicable  
polypeptide ENSMUSP00000130708 Ensembl | MGI Sequence Detail 796 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146632, MGI:2686588
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory