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Actr1b Gene Detail
Summary
  • Symbol
    Actr1b
  • Name
    ARP1 actin-related protein 1B, centractin beta
  • Synonyms
    2310066K23Rik, Arp1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917446
    NCBI Gene: 226977
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36737195-36749051 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917446
 protein coding gene Chr1:36737195-36753503 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015931
 protein coding gene Chr1:35245355-35267108 (-)
A/J MGP_AJ_G0015915
 protein coding gene Chr1:34300811-34317451 (-)
AKR/J MGP_AKRJ_G0015870
 protein coding gene Chr1:34778175-34794431 (-)
BALB/cJ MGP_BALBcJ_G0015869
 protein coding gene Chr1:33988711-34005187 (-)
C3H/HeJ MGP_C3HHeJ_G0015702
 protein coding gene Chr1:34985717-35003165 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016322
 protein coding gene Chr1:36834943-36853047 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014044
 protein coding gene Chr1:31352156-31369086 (-)
CAST/EiJ MGP_CASTEiJ_G0015283
 protein coding gene Chr1:34866409-34883608 (-)
CBA/J MGP_CBAJ_G0015674
 protein coding gene Chr1:37812218-37831270 (-)
DBA/2J MGP_DBA2J_G0015775
 protein coding gene Chr1:33635218-33651998 (-)
FVB/NJ MGP_FVBNJ_G0015777
 protein coding gene Chr1:33157651-33174884 (-)
LP/J MGP_LPJ_G0015845
 protein coding gene Chr1:35617881-35637680 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015797
 protein coding gene Chr1:40015697-40033916 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016369
 protein coding gene Chr1:34823379-34841048 (-)
PWK/PhJ MGP_PWKPhJ_G0015066
 protein coding gene Chr1:33389560-33410398 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014847
 protein coding gene Chr1:34763976-34790311 (-)
WSB/EiJ MGP_WSBEiJ_G0015345
 protein coding gene Chr1:34778211-34796062 (-)



Homology
more
  • Human Ortholog
    ACTR1B, actin related protein 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR1B, actin related protein 1B
  • Synonyms
    ARP1B, CTRN2, PC3
  • Links
    NCBI Gene ID: 10120
    neXtProt AC: NX_P42025
    UniProt: P42025

  • Chr Location
    2q11.2; chr2:97655939-97664044 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    5
  • Targeted
    3
  • Genomic Mutations
    1 involving Actr1b
  • Find Mice (IMSR)
    26 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    2
  • cDNA Data
    119
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 226977 NCBI Gene Model | MGI Sequence Detail 11857 C57BL/6J ±  kb
transcript NM_001418139 RefSeq | MGI Sequence Detail 3355 C57BL/6  
polypeptide Q8R5C5 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 119
    cDNA 119

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138136, MGI:2138359
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory