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Skic8 Gene Detail
Summary
  • Symbol
    Skic8
  • Name
    SKI8 subunit of superkiller complex
  • Synonyms
    2700038L12Rik, 2810418I05Rik, Wdr61
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917493
    NCBI Gene: 66317
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54624437-54641833 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.73 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    473 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917493
 protein coding gene Chr9:54622019-54641833 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034829
 protein coding gene Chr9:53773773-53795175 (-)
A/J MGP_AJ_G0034810
 protein coding gene Chr9:52052874-52072641 (-)
AKR/J MGP_AKRJ_G0034739
 protein coding gene Chr9:53233450-53253165 (-)
BALB/cJ MGP_BALBcJ_G0034802
 protein coding gene Chr9:51827395-51847115 (-)
C3H/HeJ MGP_C3HHeJ_G0034512
 protein coding gene Chr9:53699098-53719008 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035321
 protein coding gene Chr9:55275728-55295528 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032233
 protein coding gene Chr9:51468796-51490622 (-)
CAST/EiJ MGP_CASTEiJ_G0033834
 protein coding gene Chr9:53722365-53743512 (-)
CBA/J MGP_CBAJ_G0034483
 protein coding gene Chr9:57188468-57208225 (-)
DBA/2J MGP_DBA2J_G0034642
 protein coding gene Chr9:51944897-51964656 (-)
FVB/NJ MGP_FVBNJ_G0034584
 protein coding gene Chr9:51146564-51166476 (-)
LP/J MGP_LPJ_G0034725
 protein coding gene Chr9:54086647-54106400 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034627
 protein coding gene Chr9:58732885-58752921 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035343
 protein coding gene Chr9:53241935-53261690 (-)
PWK/PhJ MGP_PWKPhJ_G0033538
 protein coding gene Chr9:51927205-51947767 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033373
 protein coding gene Chr9:53509718-53529465 (-)
WSB/EiJ MGP_WSBEiJ_G0033946
 protein coding gene Chr9:53215866-53235609 (-)



Homology
more
  • Human Ortholog
    SKIC8, SKI8 subunit of superkiller complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SKIC8, SKI8 subunit of superkiller complex
  • Synonyms
    REC14, SKI8, WDR61
  • Links
    NCBI Gene ID: 80349
    neXtProt AC: NX_Q9GZS3
    UniProt: Q9GZS3

  • Chr Location
    15q25.1; chr15:78277835-78299703 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    7
  • cDNA Data
    15
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66317 NCBI Gene Model | MGI Sequence Detail 17397 C57BL/6J ±  kb
    transcript NM_001025375 RefSeq | MGI Sequence Detail 1331 C57BL/6  
    polypeptide Q9ERF3 UniProt | EBI | MGI Sequence Detail 305 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1913567, MGI:7382771
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:283190 Strikoudis A, et al., Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nat Cell Biol. 2016 Nov;18(11):1127-1138
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory