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Kyat1 Gene Detail
Summary
  • Symbol
    Kyat1
  • Name
    kynurenine aminotransferase 1
  • Synonyms
    2010009K05Rik, Ccbl1, cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), Kat1, KATI
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917516
    NCBI Gene: 70266
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30075136-30095859 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 21.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    475 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917516
 protein coding gene Chr2:30075136-30096307 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025558
 protein coding gene Chr2:28406302-28427481 (-)
A/J MGP_AJ_G0025536
 protein coding gene Chr2:27271178-27292496 (-)
AKR/J MGP_AKRJ_G0025505
 protein coding gene Chr2:28197547-28220310 (-)
BALB/cJ MGP_BALBcJ_G0025532
 protein coding gene Chr2:27410741-27431061 (-)
C3H/HeJ MGP_C3HHeJ_G0025293
 protein coding gene Chr2:28129346-28154748 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025977
 protein coding gene Chr2:29343924-29365905 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023385
 protein coding gene Chr2:26061980-26084397 (-)
CAST/EiJ MGP_CASTEiJ_G0024755
 protein coding gene Chr2:28019127-28046245 (-)
CBA/J MGP_CBAJ_G0025270
 protein coding gene Chr2:30337039-30361928 (-)
DBA/2J MGP_DBA2J_G0025403
 protein coding gene Chr2:27059862-27080132 (-)
FVB/NJ MGP_FVBNJ_G0025366
 protein coding gene Chr2:26872646-26894929 (-)
LP/J MGP_LPJ_G0025489
 protein coding gene Chr2:28313982-28337148 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025396
 protein coding gene Chr2:30233347-30253986 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026035
 protein coding gene Chr2:28113172-28136589 (-)
PWK/PhJ MGP_PWKPhJ_G0024502
 protein coding gene Chr2:26899200-26921571 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024302
 protein coding gene Chr2:28230357-28254250 (-)
WSB/EiJ MGP_WSBEiJ_G0024823
 protein coding gene Chr2:28244972-28265334 (-)



Homology
more
  • Human Ortholog
    KYAT1, kynurenine aminotransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KYAT1, kynurenine aminotransferase 1
  • Synonyms
    CCBL1, GTK, KAT1, KATI
  • Links
    NCBI Gene ID: 883
    neXtProt AC: NX_Q16773
    UniProt: Q16773

  • Chr Location
    9q34.11; chr9:128819663-128882523 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1064
  • Tissues
    139
  • cDNA Data
    53
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039648 Ensembl Gene Model | MGI Sequence Detail 20724 C57BL/6J ±  kb
transcript ENSMUST00000044038 Ensembl | MGI Sequence Detail 1876 Not Applicable  
polypeptide ENSMUSP00000038612 Ensembl | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138852
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory