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Ly6g6e Gene Detail
Summary
  • Symbol
    Ly6g6e
  • Name
    lymphocyte antigen 6 family member G6E
  • Synonyms
    2310011I02Rik, G6e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917524
    NCBI Gene: 70274
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35295878-35297780 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 18.59 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917524
 protein coding gene Chr17:35295843-35297781 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023614
 protein coding gene Chr17:35218218-35220120 (+)
A/J MGP_AJ_G0023574
 protein coding gene Chr17:34050650-34052545 (+)
AKR/J MGP_AKRJ_G0023542
 protein coding gene Chr17:34525225-34527117 (+)
BALB/cJ MGP_BALBcJ_G0023580
 protein coding gene Chr17:34187324-34189295 (+)
C3H/HeJ MGP_C3HHeJ_G0023341
 protein coding gene Chr17:34918018-34919962 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024019
 protein coding gene Chr17:36553650-36555552 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021500
 protein coding gene Chr17:31818460-31820339 (+)
CAST/EiJ MGP_CASTEiJ_G0022838
 protein coding gene Chr17:34920616-34922491 (+)
CBA/J MGP_CBAJ_G0023319
 protein coding gene Chr17:38060770-38062632 (+)
DBA/2J MGP_DBA2J_G0023447
 protein coding gene Chr17:33371546-33373441 (+)
FVB/NJ MGP_FVBNJ_G0023414
 protein coding gene Chr17:33208943-33210846 (+)
LP/J MGP_LPJ_G0023524
 protein coding gene Chr17:35542405-35544307 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023436
 protein coding gene Chr17:36998031-37001058 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024064
 protein coding gene Chr17:34744417-34746323 (+)
PWK/PhJ MGP_PWKPhJ_G0022585
 protein coding gene Chr17:32204492-32206426 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022405
 protein coding gene Chr17:32754783-32756699 (+)
WSB/EiJ MGP_WSBEiJ_G0022901
 protein coding gene Chr17:34863490-34865388 (+)



Homology
more
  • Human Ortholog
    LY6G6E, lymphocyte antigen 6 family member G6E (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LY6G6E, lymphocyte antigen 6 family member G6E (pseudogene)
  • Synonyms
    C6orf22, G6e
  • Links
    NCBI Gene ID: 79136

  • Chr Location
    6p21.33; chr6:31711976-31714065 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    9
  • cDNA Data
    9
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000013766 Ensembl Gene Model | MGI Sequence Detail 1903 C57BL/6J ±  kb
transcript ENSMUST00000172959 Ensembl | MGI Sequence Detail 501 Not Applicable  
polypeptide ENSMUSP00000133753 Ensembl | MGI Sequence Detail 166 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000472 Activin types I and II receptor domain
    IPR039700 Lymphocyte antigen 6G6e
    IPR045860 Snake toxin-like superfamily
Molecular
Reagents
less
  • All nucleic 12
    cDNA 9
    Primer pair 3

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:225865 Wu M, et al., Mechanisms of Inhibition and Potentiation of alpha4beta2 Nicotinic Acetylcholine Receptors by Members of the Ly6 Protein Family. J Biol Chem. 2015 Oct 2;290(40):24509-18
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory